Ragulator complex

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<StructureSection load='1stp' size='340' side='right' caption='Caption for this structure' scene=''>
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<StructureSection load='5y39' size='340' side='right' caption='Human ragulator complex proteins: LAMTOR1 coiled coil domain (grey) + LAMTOR2 roadblock domain (green) + LAMTOR3 roadblock domain (pink) + LAMTOR4 roadblock domain (yellow) + LAMTOR5 roadblock domain (magenta) PDB code [[5y39]]' scene=''>
The '''ragulator complex''' (Lamtor) is a pentamer which recruits mTORC1 in the rapamycin (mTOR) signal-transduction pathway and activates it<ref>PMID:29285400</ref>.
The '''ragulator complex''' (Lamtor) is a pentamer which recruits mTORC1 in the rapamycin (mTOR) signal-transduction pathway and activates it<ref>PMID:29285400</ref>.
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</StructureSection>
</StructureSection>
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==3D structures of ragulator complex==
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Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
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[[6b9x]] - hLAMTOR1 + LAMTOR2 + LAMTOR3 + LAMTOR4 + hepatitis B virus interacting protein - human<br />
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[[5y39]], [[5y3a]], [[6ehp]] - hLAMTOR1 + LAMTOR2 + LAMTOR3 + LAMTOR4 + LAMTOR5 <br />
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[[5x6u]] - hLAMTOR1 (mutant) + LAMTOR2 + LAMTOR3 + LAMTOR4 + LAMTOR5 <br />
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[[6ehr]] - hLAMTOR1 + LAMTOR2 + LAMTOR3 + LAMTOR4 + LAMTOR5 + Ras-related GTP-binding proteins A, C <br />
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[[5x6v]] - hLAMTOR1 (mutant) + LAMTOR2 + LAMTOR3 + LAMTOR4 + LAMTOR5 + Ras-related GTP-binding proteins A, C <br />
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[[5vok]], [[5y38]] - hLAMTOR4 + LAMTOR5<br />
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== References ==
== References ==
<references/>
<references/>
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[[Category:Topic Page]]

Revision as of 08:29, 25 October 2018

Human ragulator complex proteins: LAMTOR1 coiled coil domain (grey) + LAMTOR2 roadblock domain (green) + LAMTOR3 roadblock domain (pink) + LAMTOR4 roadblock domain (yellow) + LAMTOR5 roadblock domain (magenta) PDB code 5y39

Drag the structure with the mouse to rotate

3D structures of ragulator complex

Updated on 25-October-2018

6b9x - hLAMTOR1 + LAMTOR2 + LAMTOR3 + LAMTOR4 + hepatitis B virus interacting protein - human
5y39, 5y3a, 6ehp - hLAMTOR1 + LAMTOR2 + LAMTOR3 + LAMTOR4 + LAMTOR5
5x6u - hLAMTOR1 (mutant) + LAMTOR2 + LAMTOR3 + LAMTOR4 + LAMTOR5
6ehr - hLAMTOR1 + LAMTOR2 + LAMTOR3 + LAMTOR4 + LAMTOR5 + Ras-related GTP-binding proteins A, C
5x6v - hLAMTOR1 (mutant) + LAMTOR2 + LAMTOR3 + LAMTOR4 + LAMTOR5 + Ras-related GTP-binding proteins A, C
5vok, 5y38 - hLAMTOR4 + LAMTOR5

References

  1. ↑ Mu Z, Wang L, Deng W, Wang J, Wu G. Structural insight into the Ragulator complex which anchors mTORC1 to the lysosomal membrane. Cell Discov. 2017 Dec 26;3:17049. doi: 10.1038/celldisc.2017.49. eCollection, 2017. PMID:29285400 doi:http://dx.doi.org/10.1038/celldisc.2017.49

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Wayne Decatur

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