6ijx
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal Structure of AKR1C1 complexed with meclofenamic acid== | |
| - | + | <StructureSection load='6ijx' size='340' side='right'caption='[[6ijx]], [[Resolution|resolution]] 2.20Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[6ijx]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6IJX OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6IJX FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=JMS:2-[(2,6-DICHLORO-3-METHYL-PHENYL)AMINO]BENZOIC+ACID'>JMS</scene>, <scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene></td></tr> | |
| - | [[Category: | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[6a7a|6a7a]], [[6a7b|6a7b]]</td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6ijx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6ijx OCA], [http://pdbe.org/6ijx PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6ijx RCSB], [http://www.ebi.ac.uk/pdbsum/6ijx PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6ijx ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/AK1C1_HUMAN AK1C1_HUMAN]] Converts progesterone to its inactive form, 20-alpha-dihydroxyprogesterone (20-alpha-OHP). In the liver and intestine, may have a role in the transport of bile. May have a role in monitoring the intrahepatic bile acid concentration. Has a low bile-binding ability. May play a role in myelin formation.<ref>PMID:11013348</ref> <ref>PMID:8573067</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Chen, Y]] | ||
| + | [[Category: Hu, X]] | ||
[[Category: Zhang, H]] | [[Category: Zhang, H]] | ||
[[Category: Zhang, L]] | [[Category: Zhang, L]] | ||
[[Category: Zhao, Y]] | [[Category: Zhao, Y]] | ||
| - | [[Category: Chen, Y]] | ||
[[Category: Zheng, X]] | [[Category: Zheng, X]] | ||
| - | [[Category: | + | [[Category: Complex]] |
| + | [[Category: Inhibitor]] | ||
| + | [[Category: Oxidoreductase]] | ||
Revision as of 05:50, 16 October 2019
Crystal Structure of AKR1C1 complexed with meclofenamic acid
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Categories: Large Structures | Chen, Y | Hu, X | Zhang, H | Zhang, L | Zhao, Y | Zheng, X | Complex | Inhibitor | Oxidoreductase
