3btc

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==crystal structure of QacR(E57Q) bound to malachite green==
==crystal structure of QacR(E57Q) bound to malachite green==
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<StructureSection load='3btc' size='340' side='right' caption='[[3btc]], [[Resolution|resolution]] 2.90&Aring;' scene=''>
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<StructureSection load='3btc' size='340' side='right'caption='[[3btc]], [[Resolution|resolution]] 2.90&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3btc]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BTC OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3BTC FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3btc]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Staam Staam]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BTC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3BTC FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MGR:MALACHITE+GREEN'>MGR</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MGR:MALACHITE+GREEN'>MGR</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1jt6|1jt6]], [[1jup|1jup]], [[1jus|1jus]], [[1jty|1jty]], [[1jum|1jum]], [[1qvt|1qvt]], [[3bt9|3bt9]], [[3bti|3bti]], [[3btj|3btj]]</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1jt6|1jt6]], [[1jup|1jup]], [[1jus|1jus]], [[1jty|1jty]], [[1jum|1jum]], [[1qvt|1qvt]], [[3bt9|3bt9]], [[3bti|3bti]], [[3btj|3btj]]</div></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">qacR ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1280 Staphylococcus aureus])</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">qacR ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=158878 STAAM])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3btc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3btc OCA], [http://pdbe.org/3btc PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3btc RCSB], [http://www.ebi.ac.uk/pdbsum/3btc PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3btc ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3btc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3btc OCA], [https://pdbe.org/3btc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3btc RCSB], [https://www.ebi.ac.uk/pdbsum/3btc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3btc ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/QACR_STAAM QACR_STAAM]] Transcriptional repressor of qacA. Binds to IR1, an unusually long 28 bp operator, which is located downstream from the qacA promoter and overlaps its transcription start site. QacR is induced from its IR1 site by binding to one of many structurally dissimilar cationic lipophilic compounds, which are also substrates of QacA (By similarity).
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[[https://www.uniprot.org/uniprot/QACR_STAAM QACR_STAAM]] Transcriptional repressor of qacA. Binds to IR1, an unusually long 28 bp operator, which is located downstream from the qacA promoter and overlaps its transcription start site. QacR is induced from its IR1 site by binding to one of many structurally dissimilar cationic lipophilic compounds, which are also substrates of QacA (By similarity).
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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</div>
</div>
<div class="pdbe-citations 3btc" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 3btc" style="background-color:#fffaf0;"></div>
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==See Also==
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*[[Tetracycline repressor protein 3D structures|Tetracycline repressor protein 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Staphylococcus aureus]]
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[[Category: Large Structures]]
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[[Category: Staam]]
[[Category: Brennan, R G]]
[[Category: Brennan, R G]]
[[Category: Schumacher, M A]]
[[Category: Schumacher, M A]]

Revision as of 19:01, 20 October 2021

crystal structure of QacR(E57Q) bound to malachite green

PDB ID 3btc

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