This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
6bib
From Proteopedia
(Difference between revisions)
| Line 3: | Line 3: | ||
<StructureSection load='6bib' size='340' side='right' caption='[[6bib]], [[Resolution|resolution]] 1.95Å' scene=''> | <StructureSection load='6bib' size='340' side='right' caption='[[6bib]], [[Resolution|resolution]] 1.95Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[6bib]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6BIB OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6BIB FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[6bib]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Hu/nv/nv/1968/us Hu/nv/nv/1968/us]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6BIB OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6BIB FirstGlance]. <br> |
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=DW7:benzyl+[(9S,12S,15S)-12-(cyclohexylmethyl)-9-(hydroxymethyl)-6,11,14-trioxo-1,5,10,13,18,19-hexaazabicyclo[15.2.1]icosa-17(20),18-dien-15-yl]carbamate'>DW7</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=DW7:benzyl+[(9S,12S,15S)-12-(cyclohexylmethyl)-9-(hydroxymethyl)-6,11,14-trioxo-1,5,10,13,18,19-hexaazabicyclo[15.2.1]icosa-17(20),18-dien-15-yl]carbamate'>DW7</scene></td></tr> | ||
| + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">ORF1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=524364 Hu/NV/NV/1968/US])</td></tr> | ||
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Calicivirin Calicivirin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.22.66 3.4.22.66] </span></td></tr> | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Calicivirin Calicivirin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.22.66 3.4.22.66] </span></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6bib FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6bib OCA], [http://pdbe.org/6bib PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6bib RCSB], [http://www.ebi.ac.uk/pdbsum/6bib PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6bib ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6bib FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6bib OCA], [http://pdbe.org/6bib PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6bib RCSB], [http://www.ebi.ac.uk/pdbsum/6bib PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6bib ProSAT]</span></td></tr> | ||
| Line 15: | Line 16: | ||
</StructureSection> | </StructureSection> | ||
[[Category: Calicivirin]] | [[Category: Calicivirin]] | ||
| + | [[Category: Hu/nv/nv/1968/us]] | ||
[[Category: Battaile, K P]] | [[Category: Battaile, K P]] | ||
[[Category: Chang, K O]] | [[Category: Chang, K O]] | ||
Revision as of 07:51, 21 February 2019
1.95 A resolution structure of Norovirus 3CL protease in complex with a triazole-based macrocyclic inhibitor
| |||||||||||
Categories: Calicivirin | Hu/nv/nv/1968/us | Battaile, K P | Chang, K O | Groutas, W C | Kankanamalage, A C.G | Kim, Y | Lovell, S | Mehzabeen, N | Rathnayake, A D | Weerawarna, P M | Antiviral inhibitor | Hydrolase-hydrolase inhibitor complex | Norovirus | Norwalk virus | Protease | Triazole-based macrocyclic inhibitor
