6bic
From Proteopedia
(Difference between revisions)
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<StructureSection load='6bic' size='340' side='right' caption='[[6bic]], [[Resolution|resolution]] 2.25Å' scene=''> | <StructureSection load='6bic' size='340' side='right' caption='[[6bic]], [[Resolution|resolution]] 2.25Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
- | <table><tr><td colspan='2'>[[6bic]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6BIC OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6BIC FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[6bic]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Hu/nv/nv/1968/us Hu/nv/nv/1968/us]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6BIC OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6BIC FirstGlance]. <br> |
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=5LH:(PHENYLMETHYL)+~{N}-[(9~{S},12~{S},15~{S})-9-(HYDROXYMETHYL)-12-(2-METHYLPROPYL)-6,11,14-TRIS(OXIDANYLIDENE)-1,5,10,13,18,19-HEXAZABICYCLO[15.2.1]ICOSA-17(20),18-DIEN-15-YL]CARBAMATE'>5LH</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=5LH:(PHENYLMETHYL)+~{N}-[(9~{S},12~{S},15~{S})-9-(HYDROXYMETHYL)-12-(2-METHYLPROPYL)-6,11,14-TRIS(OXIDANYLIDENE)-1,5,10,13,18,19-HEXAZABICYCLO[15.2.1]ICOSA-17(20),18-DIEN-15-YL]CARBAMATE'>5LH</scene></td></tr> | ||
+ | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">ORF1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=524364 Hu/NV/NV/1968/US])</td></tr> | ||
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Calicivirin Calicivirin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.22.66 3.4.22.66] </span></td></tr> | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Calicivirin Calicivirin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.22.66 3.4.22.66] </span></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6bic FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6bic OCA], [http://pdbe.org/6bic PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6bic RCSB], [http://www.ebi.ac.uk/pdbsum/6bic PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6bic ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6bic FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6bic OCA], [http://pdbe.org/6bic PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6bic RCSB], [http://www.ebi.ac.uk/pdbsum/6bic PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6bic ProSAT]</span></td></tr> | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Calicivirin]] | [[Category: Calicivirin]] | ||
+ | [[Category: Hu/nv/nv/1968/us]] | ||
[[Category: Battaile, K P]] | [[Category: Battaile, K P]] | ||
[[Category: Chang, K O]] | [[Category: Chang, K O]] |
Revision as of 07:51, 21 February 2019
2.25 A resolution structure of Norovirus 3CL protease in complex with a triazole-based macrocyclic inhibitor
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Categories: Calicivirin | Hu/nv/nv/1968/us | Battaile, K P | Chang, K O | Groutas, W C | Kankanamalage, A C.G | Kim, Y | Lovell, S | Mehzabeen, N | Rathnayake, A D | Weerawarna, P M | Antiviral inhibitor | Hydrolase-hydrolase inhibitor complex | Norovirus | Norwalk virus | Protease | Triazole-based macrocyclic inhibitor