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3cns
From Proteopedia
(Difference between revisions)
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==Crystal structure of fms1 in complex with S-Bz-MeSpermidine== | ==Crystal structure of fms1 in complex with S-Bz-MeSpermidine== | ||
| - | <StructureSection load='3cns' size='340' side='right' caption='[[3cns]], [[Resolution|resolution]] 2.40Å' scene=''> | + | <StructureSection load='3cns' size='340' side='right'caption='[[3cns]], [[Resolution|resolution]] 2.40Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[3cns]] is a 2 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[3cns]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Atcc_18824 Atcc 18824]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3CNS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3CNS FirstGlance]. <br> |
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=SP8:N-{(1S)-3-[(4-AMINOBUTYL)AMINO]-1-METHYLPROPYL}BENZAMIDE'>SP8</scene></td></tr> | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=SP8:N-{(1S)-3-[(4-AMINOBUTYL)AMINO]-1-METHYLPROPYL}BENZAMIDE'>SP8</scene></td></tr> |
| - | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1yy5|1yy5]], [[1xpq|1xpq]], [[3cn8|3cn8]], [[3cnd|3cnd]], [[3cnp|3cnp]], [[3cnt|3cnt]]</td></tr> | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1yy5|1yy5]], [[1xpq|1xpq]], [[3cn8|3cn8]], [[3cnd|3cnd]], [[3cnp|3cnp]], [[3cnt|3cnt]]</div></td></tr> |
| - | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">fms1 ([ | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">fms1 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=4932 ATCC 18824])</td></tr> |
| - | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Oxidoreductase Oxidoreductase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.5.3.13, 1.5.3.14, 1.5.3.15, 1.5.3.16 and 1.5.3.17 1.5.3.13, 1.5.3.14, 1.5.3.15, 1.5.3.16 and 1.5.3.17] </span></td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3cns FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3cns OCA], [https://pdbe.org/3cns PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3cns RCSB], [https://www.ebi.ac.uk/pdbsum/3cns PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3cns ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [[ | + | [[https://www.uniprot.org/uniprot/FMS1_YEAST FMS1_YEAST]] Involved in the production of beta-alanine, a precursor of pantothenic acid. Multicopy suppressor of fenpropimorph resistance.<ref>PMID:12670477</ref> <ref>PMID:14617780</ref> |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Atcc 18824]] | [[Category: Atcc 18824]] | ||
| + | [[Category: Large Structures]] | ||
[[Category: Oxidoreductase]] | [[Category: Oxidoreductase]] | ||
[[Category: Hao, H]] | [[Category: Hao, H]] | ||
Revision as of 08:02, 27 January 2022
Crystal structure of fms1 in complex with S-Bz-MeSpermidine
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