3c38
From Proteopedia
(Difference between revisions)
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==Crystal structure of the periplasmic domain of Vibrio Cholerae LuxQ== | ==Crystal structure of the periplasmic domain of Vibrio Cholerae LuxQ== | ||
| - | <StructureSection load='3c38' size='340' side='right' caption='[[3c38]], [[Resolution|resolution]] 2.30Å' scene=''> | + | <StructureSection load='3c38' size='340' side='right'caption='[[3c38]], [[Resolution|resolution]] 2.30Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[3c38]] is a 1 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[3c38]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/"bacillo_virgola_del_koch"_trevisan_1884 "bacillo virgola del koch" trevisan 1884]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3C38 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3C38 FirstGlance]. <br> |
| - | </td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3c30|3c30]]</td></tr> | + | </td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3c30|3c30]]</div></td></tr> |
| - | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">luxQ ([ | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">luxQ ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=666 "Bacillo virgola del Koch" Trevisan 1884])</td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3c38 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3c38 OCA], [https://pdbe.org/3c38 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3c38 RCSB], [https://www.ebi.ac.uk/pdbsum/3c38 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3c38 ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [[ | + | [[https://www.uniprot.org/uniprot/LUXQ_VIBCH LUXQ_VIBCH]] At low cell density, in absence of AI-2 (autoinducer 2), LuxQ has a kinase activity and autophosphorylates on a histidine residue. The phosphoryl group is then transferred to an aspartate residue in the response regulator domain. The phosphoryl group is transferred to LuxU, and ultimately to LuxO. At high cell density, in the presence of AI-2, the kinase activity is inactivated, and the response regulator domain has a phosphatase activity (By similarity). |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Bacillo virgola del koch trevisan 1884]] | [[Category: Bacillo virgola del koch trevisan 1884]] | ||
| + | [[Category: Large Structures]] | ||
[[Category: Hendrickson, W]] | [[Category: Hendrickson, W]] | ||
[[Category: Slama, B]] | [[Category: Slama, B]] | ||
Revision as of 07:41, 27 January 2022
Crystal structure of the periplasmic domain of Vibrio Cholerae LuxQ
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Categories: Bacillo virgola del koch trevisan 1884 | Large Structures | Hendrickson, W | Slama, B | 2-component system | Histidine kinase | Hydrolase | Inner membrane | Membrane | Phosphoprotein | Protein phosphatase | Quorum sensing | Signaling protein | Transferase | Transmembrane | Two-component regulatory system
