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3c0n
From Proteopedia
(Difference between revisions)
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==Crystal structure of the proaerolysin mutant Y221G at 2.2 A== | ==Crystal structure of the proaerolysin mutant Y221G at 2.2 A== | ||
| - | <StructureSection load='3c0n' size='340' side='right' caption='[[3c0n]], [[Resolution|resolution]] 2.20Å' scene=''> | + | <StructureSection load='3c0n' size='340' side='right'caption='[[3c0n]], [[Resolution|resolution]] 2.20Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[3c0n]] is a 2 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[3c0n]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/"aeromonas_liquefaciens"_kluyver_and_van_niel_1936 "aeromonas liquefaciens" kluyver and van niel 1936]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3C0N OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3C0N FirstGlance]. <br> |
| - | </td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3c0m|3c0m]], [[3c0o|3c0o]], [[1pre|1pre]]</td></tr> | + | </td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3c0m|3c0m]], [[3c0o|3c0o]], [[1pre|1pre]]</div></td></tr> |
| - | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">aerA ([ | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">aerA ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=644 "Aeromonas liquefaciens" Kluyver and van Niel 1936])</td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3c0n FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3c0n OCA], [https://pdbe.org/3c0n PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3c0n RCSB], [https://www.ebi.ac.uk/pdbsum/3c0n PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3c0n ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [[ | + | [[https://www.uniprot.org/uniprot/AERA_AERHY AERA_AERHY]] Aerolysin is a cytolytic toxin exported by the Gram negative Aeromonas bacteria. The mature toxin binds to eukaryotic cells and aggregates to form holes approximately 3 nm in diameter, leading to destruction of the membrane permeability barrier and osmotic lysis. |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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==See Also== | ==See Also== | ||
| - | *[[Aerolysin|Aerolysin]] | + | *[[Aerolysin 3D structures|Aerolysin 3D structures]] |
== References == | == References == | ||
<references/> | <references/> | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Aeromonas liquefaciens kluyver and van niel 1936]] | [[Category: Aeromonas liquefaciens kluyver and van niel 1936]] | ||
| + | [[Category: Large Structures]] | ||
[[Category: Burr, S E]] | [[Category: Burr, S E]] | ||
[[Category: Goot, G van der]] | [[Category: Goot, G van der]] | ||
Revision as of 07:28, 10 November 2021
Crystal structure of the proaerolysin mutant Y221G at 2.2 A
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