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3cky
From Proteopedia
(Difference between revisions)
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==Structural and Kinetic Properties of a beta-hydroxyacid dehydrogenase involved in nicotinate fermentation== | ==Structural and Kinetic Properties of a beta-hydroxyacid dehydrogenase involved in nicotinate fermentation== | ||
| - | <StructureSection load='3cky' size='340' side='right' caption='[[3cky]], [[Resolution|resolution]] 2.30Å' scene=''> | + | <StructureSection load='3cky' size='340' side='right'caption='[[3cky]], [[Resolution|resolution]] 2.30Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[3cky]] is a 4 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[3cky]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Eubacterium_barkeri Eubacterium barkeri]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3CKY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3CKY FirstGlance]. <br> |
| - | </td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Hgd ([ | + | </td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Hgd ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1528 Eubacterium barkeri])</td></tr> |
| - | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/2-hydroxymethylglutarate_dehydrogenase 2-hydroxymethylglutarate dehydrogenase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.291 1.1.1.291] </span></td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3cky FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3cky OCA], [https://pdbe.org/3cky PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3cky RCSB], [https://www.ebi.ac.uk/pdbsum/3cky PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3cky ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [[ | + | [[https://www.uniprot.org/uniprot/HMGD_EUBBA HMGD_EUBBA]] Catalyzes the conversion of 2-formylglutarate to (S)-2-hydroxymethylglutarate. Has very low activity with (S)-3-hydroxyisobutyrate.<ref>PMID:18680749</ref> |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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[[Category: 2-hydroxymethylglutarate dehydrogenase]] | [[Category: 2-hydroxymethylglutarate dehydrogenase]] | ||
[[Category: Eubacterium barkeri]] | [[Category: Eubacterium barkeri]] | ||
| + | [[Category: Large Structures]] | ||
[[Category: Alhapel, A]] | [[Category: Alhapel, A]] | ||
[[Category: Essen, L O]] | [[Category: Essen, L O]] | ||
Revision as of 07:59, 27 January 2022
Structural and Kinetic Properties of a beta-hydroxyacid dehydrogenase involved in nicotinate fermentation
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