6bo5

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'''Unreleased structure'''
 
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The entry 6bo5 is ON HOLD until Paper Publication
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==TRPV2 ion channel in partially closed state==
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<StructureSection load='6bo5' size='340' side='right' caption='[[6bo5]], [[Resolution|resolution]] 3.60&Aring;' scene=''>
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Authors:
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== Structural highlights ==
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<table><tr><td colspan='2'>[[6bo5]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6BO5 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6BO5 FirstGlance]. <br>
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Description:
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</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[6bo4|6bo4]]</td></tr>
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[[Category: Unreleased Structures]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6bo5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6bo5 OCA], [http://pdbe.org/6bo5 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6bo5 RCSB], [http://www.ebi.ac.uk/pdbsum/6bo5 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6bo5 ProSAT]</span></td></tr>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/TRPV2_RAT TRPV2_RAT]] Calcium-permeable, non-selective cation channel with an outward rectification. Seems to be regulated, at least in part, by growth factors, like IGF1, PDGF and morphogenetic neuropeptide/head activator. May transduce physical stimuli in mast cells. Activated by temperatures higher than 52 degrees Celsius; is not activated by vanilloids and acidic pH (By similarity).<ref>PMID:10201375</ref> <ref>PMID:15249591</ref>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Dosey, T L]]
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[[Category: Wang, Z]]
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[[Category: Cation]]
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[[Category: Channel]]
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[[Category: Closed]]
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[[Category: Membrane protein]]
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[[Category: Trp]]

Revision as of 06:32, 5 December 2018

TRPV2 ion channel in partially closed state

6bo5, resolution 3.60Å

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