6ffm

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Current revision (05:13, 21 November 2024) (edit) (undo)
 
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==Crystal Structure of Human KEAP1 BTB Domain in Complex with isoxazoline-based inhibitor==
==Crystal Structure of Human KEAP1 BTB Domain in Complex with isoxazoline-based inhibitor==
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<StructureSection load='6ffm' size='340' side='right' caption='[[6ffm]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
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<StructureSection load='6ffm' size='340' side='right'caption='[[6ffm]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[6ffm]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6FFM OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6FFM FirstGlance]. <br>
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<table><tr><td colspan='2'>[[6ffm]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6FFM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6FFM FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=D8N:~{N}-[4-[(5~{R})-4,5-dihydro-1,2-oxazol-5-yl]phenyl]ethanamide'>D8N</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6ffm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6ffm OCA], [http://pdbe.org/6ffm PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6ffm RCSB], [http://www.ebi.ac.uk/pdbsum/6ffm PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6ffm ProSAT]</span></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=D8N:~{N}-[4-[(5~{R})-4,5-dihydro-1,2-oxazol-5-yl]phenyl]ethanamide'>D8N</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6ffm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6ffm OCA], [https://pdbe.org/6ffm PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6ffm RCSB], [https://www.ebi.ac.uk/pdbsum/6ffm PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6ffm ProSAT]</span></td></tr>
</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/KEAP1_HUMAN KEAP1_HUMAN]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</div>
</div>
<div class="pdbe-citations 6ffm" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 6ffm" style="background-color:#fffaf0;"></div>
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==See Also==
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*[[Kelch-like protein 3D structures|Kelch-like protein 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Moniot, S]]
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[[Category: Homo sapiens]]
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[[Category: Steegborn, C]]
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[[Category: Large Structures]]
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[[Category: 3-bromo-4 5-dihydroisoxazole]]
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[[Category: Moniot S]]
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[[Category: Antioxidant response]]
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[[Category: Steegborn C]]
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[[Category: Btb domain]]
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[[Category: Signaling protein]]
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Current revision

Crystal Structure of Human KEAP1 BTB Domain in Complex with isoxazoline-based inhibitor

PDB ID 6ffm

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