2p1j

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==Crystal structure of a polC-type DNA polymerase III exonuclease domain from Thermotoga maritima==
==Crystal structure of a polC-type DNA polymerase III exonuclease domain from Thermotoga maritima==
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<StructureSection load='2p1j' size='340' side='right' caption='[[2p1j]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
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<StructureSection load='2p1j' size='340' side='right'caption='[[2p1j]]' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2p1j]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Thema Thema]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2P1J OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2P1J FirstGlance]. <br>
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<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2P1J OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2P1J FirstGlance]. <br>
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</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">polC, TM_0576 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=243274 THEMA])</td></tr>
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2p1j FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2p1j OCA], [https://pdbe.org/2p1j PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2p1j RCSB], [https://www.ebi.ac.uk/pdbsum/2p1j PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2p1j ProSAT], [https://www.topsan.org/Proteins/NYSGXRC/2p1j TOPSAN]</span></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/DNA-directed_DNA_polymerase DNA-directed DNA polymerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.7 2.7.7.7] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2p1j FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2p1j OCA], [http://pdbe.org/2p1j PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2p1j RCSB], [http://www.ebi.ac.uk/pdbsum/2p1j PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2p1j ProSAT], [http://www.topsan.org/Proteins/NYSGXRC/2p1j TOPSAN]</span></td></tr>
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</table>
</table>
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== Function ==
 
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[[http://www.uniprot.org/uniprot/DPO3_THEMA DPO3_THEMA]] Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity.
 
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2p1j ConSurf].
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2p1j ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
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==See Also==
 
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*[[DNA polymerase|DNA polymerase]]
 
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: DNA-directed DNA polymerase]]
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[[Category: Large Structures]]
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[[Category: Thema]]
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[[Category: Almo SC]]
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[[Category: Almo, S C]]
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[[Category: Bain KT]]
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[[Category: Bain, K T]]
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[[Category: Bonanno JB]]
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[[Category: Bonanno, J B]]
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[[Category: Burley SK]]
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[[Category: Burley, S K]]
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[[Category: Izuka M]]
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[[Category: Izuka, M]]
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[[Category: Rutter M]]
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[[Category: Structural genomic]]
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[[Category: Sauder JM]]
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[[Category: Rutter, M]]
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[[Category: Smith D]]
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[[Category: Sauder, J M]]
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[[Category: Sridhar V]]
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[[Category: Smith, D]]
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[[Category: Wasserman S]]
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[[Category: Sridhar, V]]
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[[Category: Wasserman, S]]
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[[Category: Exonuclease]]
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[[Category: NYSGXRC, New York SGX Research Center for Structural Genomics]]
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[[Category: PSI, Protein structure initiative]]
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[[Category: Transferase]]
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Revision as of 13:11, 9 June 2021

Crystal structure of a polC-type DNA polymerase III exonuclease domain from Thermotoga maritima

PDB ID 2p1j

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