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3e9v

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==Crystal structure of human B-cell Translocation Gene 2 (BTG2)==
==Crystal structure of human B-cell Translocation Gene 2 (BTG2)==
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<StructureSection load='3e9v' size='340' side='right' caption='[[3e9v]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
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<StructureSection load='3e9v' size='340' side='right'caption='[[3e9v]]' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3e9v]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3E9V OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3E9V FirstGlance]. <br>
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<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3E9V OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3E9V FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr>
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3e9v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3e9v OCA], [https://pdbe.org/3e9v PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3e9v RCSB], [https://www.ebi.ac.uk/pdbsum/3e9v PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3e9v ProSAT], [https://www.topsan.org/Proteins/NYSGXRC/3e9v TOPSAN]</span></td></tr>
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<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">BTG2, PC3 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3e9v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3e9v OCA], [http://pdbe.org/3e9v PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3e9v RCSB], [http://www.ebi.ac.uk/pdbsum/3e9v PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3e9v ProSAT], [http://www.topsan.org/Proteins/NYSGXRC/3e9v TOPSAN]</span></td></tr>
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</table>
</table>
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== Function ==
 
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[[http://www.uniprot.org/uniprot/BTG2_HUMAN BTG2_HUMAN]] Involved in cell cycle regulation. Could be involved in the growth arrest and differentiation of the neuronal precursors (By similarity). Anti-proliferative protein. Modulates transcription regulation mediated by ESR1. Involved in mitochondrial depolarization and neurite outgrowth.<ref>PMID:12771185</ref> <ref>PMID:15788397</ref> <ref>PMID:18773938</ref>
 
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3e9v ConSurf].
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3e9v ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
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== References ==
 
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<references/>
 
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Human]]
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[[Category: Large Structures]]
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[[Category: Atwell, S]]
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[[Category: Atwell S]]
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[[Category: Burley, S K]]
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[[Category: Burley SK]]
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[[Category: Freeman, J]]
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[[Category: Freeman J]]
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[[Category: Hu, S]]
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[[Category: Hu S]]
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[[Category: Maletic, M]]
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[[Category: Maletic M]]
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[[Category: Structural genomic]]
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[[Category: Romero R]]
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[[Category: Romero, R]]
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[[Category: Sampathkumar P]]
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[[Category: Sampathkumar, P]]
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[[Category: Sauder JM]]
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[[Category: Sauder, J M]]
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[[Category: Tarun G]]
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[[Category: Tarun, G]]
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[[Category: Wasserman S]]
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[[Category: Wasserman, S]]
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[[Category: Antiproliferative protein]]
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[[Category: B-cell translocation gene 2]]
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[[Category: Btg2]]
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[[Category: NYSGXRC, New York SGX Research Center for Structural Genomics]]
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[[Category: PSI, Protein structure initiative]]
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[[Category: Transcription]]
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[[Category: Transcription regulation]]
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[[Category: Transcription regulator]]
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[[Category: Tumour supressor]]
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Revision as of 11:44, 16 February 2022

Crystal structure of human B-cell Translocation Gene 2 (BTG2)

PDB ID 3e9v

Drag the structure with the mouse to rotate

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