2vkr

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[[Image:2vkr.jpg|left|200px]]
[[Image:2vkr.jpg|left|200px]]
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{{Structure
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<!--
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|PDB= 2vkr |SIZE=350|CAPTION= <scene name='initialview01'>2vkr</scene>, resolution 2.01&Aring;
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The line below this paragraph, containing "STRUCTURE_2vkr", creates the "Structure Box" on the page.
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|SITE= <scene name='pdbsite=AC1:F3s+Binding+Site+For+Chain+A'>AC1</scene>, <scene name='pdbsite=AC2:Sf4+Binding+Site+For+Chain+A'>AC2</scene>, <scene name='pdbsite=AC3:Zn+Binding+Site+For+Chain+A'>AC3</scene>, <scene name='pdbsite=AC4:F3s+Binding+Site+For+Chain+B'>AC4</scene>, <scene name='pdbsite=AC5:Sf4+Binding+Site+For+Chain+B'>AC5</scene>, <scene name='pdbsite=AC6:Zn+Binding+Site+For+Chain+B'>AC6</scene>, <scene name='pdbsite=AC7:F3s+Binding+Site+For+Chain+C'>AC7</scene>, <scene name='pdbsite=AC8:Sf4+Binding+Site+For+Chain+C'>AC8</scene>, <scene name='pdbsite=AC9:Zn+Binding+Site+For+Chain+C'>AC9</scene>, <scene name='pdbsite=BC1:F3s+Binding+Site+For+Chain+D'>BC1</scene>, <scene name='pdbsite=BC2:Sf4+Binding+Site+For+Chain+D'>BC2</scene>, <scene name='pdbsite=BC3:Zn+Binding+Site+For+Chain+D'>BC3</scene>, <scene name='pdbsite=BC4:F3s+Binding+Site+For+Chain+E'>BC4</scene>, <scene name='pdbsite=BC5:Sf4+Binding+Site+For+Chain+E'>BC5</scene>, <scene name='pdbsite=BC6:Zn+Binding+Site+For+Chain+E'>BC6</scene>, <scene name='pdbsite=BC7:F3s+Binding+Site+For+Chain+F'>BC7</scene>, <scene name='pdbsite=BC8:Sf4+Binding+Site+For+Chain+F'>BC8</scene>, <scene name='pdbsite=BC9:Zn+Binding+Site+For+Chain+F'>BC9</scene>, <scene name='pdbsite=CC1:F3s+Binding+Site+For+Chain+G'>CC1</scene>, <scene name='pdbsite=CC2:Sf4+Binding+Site+For+Chain+G'>CC2</scene> and <scene name='pdbsite=CC3:Zn+Binding+Site+For+Chain+G'>CC3</scene>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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|LIGAND= <scene name='pdbligand=F3S:FE3-S4+CLUSTER'>F3S</scene>, <scene name='pdbligand=SF4:IRON/SULFUR+CLUSTER'>SF4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene>
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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|ACTIVITY=
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or leave the SCENE parameter empty for the default display.
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|GENE=
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-->
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|DOMAIN=
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{{STRUCTURE_2vkr| PDB=2vkr | SCENE= }}
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|RELATEDENTRY=
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2vkr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vkr OCA], [http://www.ebi.ac.uk/pdbsum/2vkr PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2vkr RCSB]</span>
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}}
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'''3FE-4S, 4FE-4S PLUS ZN ACIDIANUS AMBIVALENS FERREDOXIN'''
'''3FE-4S, 4FE-4S PLUS ZN ACIDIANUS AMBIVALENS FERREDOXIN'''
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[[Category: 3fe-4]]
[[Category: 3fe-4]]
[[Category: 4fe-4]]
[[Category: 4fe-4]]
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[[Category: electron transport]]
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[[Category: Electron transport]]
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[[Category: ferredoxin]]
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[[Category: Ferredoxin]]
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[[Category: hemihedric twinnig]]
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[[Category: Hemihedric twinnig]]
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[[Category: iron]]
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[[Category: Iron]]
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[[Category: iron-sulfur]]
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[[Category: Iron-sulfur]]
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[[Category: iron-sulfur protein]]
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[[Category: Iron-sulfur protein]]
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[[Category: metal-binding]]
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[[Category: Metal-binding]]
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[[Category: methylation]]
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[[Category: Methylation]]
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[[Category: protein folding]]
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[[Category: Protein folding]]
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[[Category: thermophile]]
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[[Category: Thermophile]]
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[[Category: thermostable protein]]
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[[Category: Thermostable protein]]
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[[Category: transport]]
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[[Category: Transport]]
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[[Category: zinc]]
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[[Category: Zinc]]
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[[Category: zn center]]
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[[Category: Zn center]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun May 4 18:58:05 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 05:13:19 2008''
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Revision as of 15:58, 4 May 2008

Image:2vkr.jpg

Template:STRUCTURE 2vkr

3FE-4S, 4FE-4S PLUS ZN ACIDIANUS AMBIVALENS FERREDOXIN


Overview

Detailed structural models of di-cluster seven-iron ferredoxins constitute a valuable resource for folding and stability studies relating the metal cofactors' role in protein stability. The here reported, hemihedric twinned crystal structure at 2.0A resolution from Acidianus ambivalens ferredoxin, shows an integral 103 residues, physiologically relevant native form composed by a N-terminal extension comprising a His/Asp Zn(2+) site and the ferredoxin (betaalphabeta)(2) core, which harbours intact clusters I and II, a [3Fe-4S](1+/0) and a [4Fe-4S](2+/1+) centres. This is in contrast with the previously available ferredoxin structure from Sulfolofus tokodai, which was obtained from an artificial oxidative conversion with two [3Fe-4S](1+/0) centres and poor definition around cluster II.

About this Structure

2VKR is a Single protein structure of sequence from Acidianus ambivalens. Full crystallographic information is available from OCA.

Reference

Crystallographic analysis of the intact metal centres [3Fe-4S](1+/0) and [4Fe-4S](2+/1+) in a Zn(2+)-containing ferredoxin., Frazao C, Aragao D, Coelho R, Leal SS, Gomes CM, Teixeira M, Carrondo MA, FEBS Lett. 2008 Mar 5;582(5):763-7. Epub 2008 Feb 5. PMID:18258200 Page seeded by OCA on Sun May 4 18:58:05 2008

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OCA

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