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3drx
From Proteopedia
(Difference between revisions)
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==X-ray crystal structure of human KCTD5 protein crystallized in high-salt buffer== | ==X-ray crystal structure of human KCTD5 protein crystallized in high-salt buffer== | ||
| - | <StructureSection load='3drx' size='340' side='right' caption='[[3drx]], [[Resolution|resolution]] 3.11Å' scene=''> | + | <StructureSection load='3drx' size='340' side='right'caption='[[3drx]], [[Resolution|resolution]] 3.11Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[3drx]] is a 5 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[3drx]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3DRX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3DRX FirstGlance]. <br> |
| - | </td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3dry|3dry]], [[3drz|3drz]]</td></tr> | + | </td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3dry|3dry]], [[3drz|3drz]]</div></td></tr> |
| - | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">KCTD5 ([ | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">KCTD5 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3drx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3drx OCA], [https://pdbe.org/3drx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3drx RCSB], [https://www.ebi.ac.uk/pdbsum/3drx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3drx ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [[ | + | [[https://www.uniprot.org/uniprot/KCTD5_HUMAN KCTD5_HUMAN]] Its interaction with CUL3 suggests that it may act as a substrate adapter in some E3 ligase complex. Does not affect the function of Kv channel Kv2.1/KCNB1, Kv1.2/KCNA2, Kv4.2/KCND2 and Kv3.4/KCNC4.<ref>PMID:18573101</ref> |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Human]] | [[Category: Human]] | ||
| + | [[Category: Large Structures]] | ||
[[Category: Dementieva, I]] | [[Category: Dementieva, I]] | ||
[[Category: Goldstein, S A.N]] | [[Category: Goldstein, S A.N]] | ||
Current revision
X-ray crystal structure of human KCTD5 protein crystallized in high-salt buffer
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