6hzn

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'''Unreleased structure'''
 
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The entry 6hzn is ON HOLD until Paper Publication
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==Crystal structure of human dermatan sulfate epimerase 1==
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<StructureSection load='6hzn' size='340' side='right'caption='[[6hzn]], [[Resolution|resolution]] 2.41&Aring;' scene=''>
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Authors: Hasan, M., Unge, J., Westergren-Thorsson, G., Ellervik, U., Mueller, U., Malmstrom, A., Tykesson, E.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[6hzn]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6HZN OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6HZN FirstGlance]. <br>
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Description: Crystal structure of human dermatan sulfate epimerase 1
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene>, <scene name='pdbligand=MES:2-(N-MORPHOLINO)-ETHANESULFONIC+ACID'>MES</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
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[[Category: Unreleased Structures]]
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Chondroitin-glucuronate_5-epimerase Chondroitin-glucuronate 5-epimerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.1.3.19 5.1.3.19] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6hzn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6hzn OCA], [http://pdbe.org/6hzn PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6hzn RCSB], [http://www.ebi.ac.uk/pdbsum/6hzn PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6hzn ProSAT]</span></td></tr>
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</table>
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== Disease ==
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[[http://www.uniprot.org/uniprot/DSE_HUMAN DSE_HUMAN]] Musculocontractural Ehlers-Danlos syndrome. The disease is caused by mutations affecting the gene represented in this entry.
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== Function ==
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[[http://www.uniprot.org/uniprot/DSE_HUMAN DSE_HUMAN]] Converts D-glucuronic acid to L-iduronic acid (IdoUA) residues.<ref>PMID:16505484</ref>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Chondroitin-glucuronate 5-epimerase]]
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[[Category: Large Structures]]
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[[Category: Ellervik, U]]
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[[Category: Hasan, M]]
[[Category: Malmstrom, A]]
[[Category: Malmstrom, A]]
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[[Category: Mueller, U]]
[[Category: Tykesson, E]]
[[Category: Tykesson, E]]
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[[Category: Hasan, M]]
 
[[Category: Unge, J]]
[[Category: Unge, J]]
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[[Category: Mueller, U]]
 
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[[Category: Ellervik, U]]
 
[[Category: Westergren-Thorsson, G]]
[[Category: Westergren-Thorsson, G]]
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[[Category: Biosynthetic protein]]
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[[Category: Chondroitin sulfate]]
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[[Category: Dermatan sulfate]]
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[[Category: Epimerase]]
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[[Category: Glycosaminoglycan]]
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[[Category: Golgi]]
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[[Category: Isomerase]]

Revision as of 16:05, 22 January 2020

Crystal structure of human dermatan sulfate epimerase 1

PDB ID 6hzn

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