6i8b
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of Spindlin1 in complex with the inhibitor VinSpinIn== | |
| - | + | <StructureSection load='6i8b' size='340' side='right' caption='[[6i8b]], [[Resolution|resolution]] 1.76Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[6i8b]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6I8B OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6I8B FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=GLY:GLYCINE'>GLY</scene>, <scene name='pdbligand=H7T:2-[4-[2-[[2-[3-[2-azanyl-5-(cyclopropylmethoxy)-3,3-dimethyl-indol-6-yl]oxypropyl]-1,3-dihydroisoindol-5-yl]oxy]ethyl]-1,2,3-triazol-1-yl]-1-[4-(2-pyrrolidin-1-ylethyl)piperidin-1-yl]ethanone'>H7T</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr> | |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6i8b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6i8b OCA], [http://pdbe.org/6i8b PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6i8b RCSB], [http://www.ebi.ac.uk/pdbsum/6i8b PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6i8b ProSAT]</span></td></tr> |
| - | [[Category: | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/SPIN1_HUMAN SPIN1_HUMAN]] May play a role in cell-cycle regulation during the transition from gamete to embryo (By similarity). | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Arrowsmith, C H]] | ||
| + | [[Category: Bountra, C]] | ||
| + | [[Category: Brennan, P E]] | ||
| + | [[Category: Edwards, A]] | ||
[[Category: Fagan, V]] | [[Category: Fagan, V]] | ||
| - | [[Category: Oppermann, U.C.T]] | ||
[[Category: Johansson, C]] | [[Category: Johansson, C]] | ||
| - | [[Category: Brennan, P.E]] | ||
| - | [[Category: Edwards, A]] | ||
[[Category: Krojer, T]] | [[Category: Krojer, T]] | ||
| - | [[Category: | + | [[Category: Oppermann, U C.T]] |
| - | [[Category: Sorrell, F | + | [[Category: Sorrell, F J]] |
| + | [[Category: Cell cycle]] | ||
| + | [[Category: Epigenetic]] | ||
| + | [[Category: Methyl-arginine]] | ||
| + | [[Category: Methyl-lysine]] | ||
| + | [[Category: Tudor domain]] | ||
Revision as of 06:48, 5 December 2018
Crystal structure of Spindlin1 in complex with the inhibitor VinSpinIn
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