6n2u
From Proteopedia
(Difference between revisions)
m (Protected "6n2u" [edit=sysop:move=sysop]) |
|||
Line 1: | Line 1: | ||
- | '''Unreleased structure''' | ||
- | + | ==IL-8 Structure from Bacterial Expression Source== | |
- | + | <StructureSection load='6n2u' size='340' side='right'caption='[[6n2u]], [[Resolution|resolution]] 1.25Å' scene=''> | |
- | + | == Structural highlights == | |
- | + | <table><tr><td colspan='2'>[[6n2u]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6N2U OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6N2U FirstGlance]. <br> | |
- | + | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6n2u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6n2u OCA], [http://pdbe.org/6n2u PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6n2u RCSB], [http://www.ebi.ac.uk/pdbsum/6n2u PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6n2u ProSAT]</span></td></tr> | |
- | [[Category: | + | </table> |
- | [[Category: Luo, J | + | == Function == |
+ | [[http://www.uniprot.org/uniprot/IL8_HUMAN IL8_HUMAN]] IL-8 is a chemotactic factor that attracts neutrophils, basophils, and T-cells, but not monocytes. It is also involved in neutrophil activation. It is released from several cell types in response to an inflammatory stimulus. IL-8(6-77) has a 5-10-fold higher activity on neutrophil activation, IL-8(5-77) has increased activity on neutrophil activation and IL-8(7-77) has a higher affinity to receptors CXCR1 and CXCR2 as compared to IL-8(1-77), respectively.<ref>PMID:2145175</ref> <ref>PMID:2212672</ref> <ref>PMID:11978786</ref> | ||
+ | == References == | ||
+ | <references/> | ||
+ | __TOC__ | ||
+ | </StructureSection> | ||
+ | [[Category: Large Structures]] | ||
+ | [[Category: Jung, J H]] | ||
+ | [[Category: Luo, J L]] | ||
[[Category: Park, H]] | [[Category: Park, H]] | ||
- | [[Category: | + | [[Category: Il-8]] |
+ | [[Category: Immune system]] |
Revision as of 15:25, 20 November 2019
IL-8 Structure from Bacterial Expression Source
|
Categories: Large Structures | Jung, J H | Luo, J L | Park, H | Il-8 | Immune system