2z2s

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
[[Image:2z2s.jpg|left|200px]]
[[Image:2z2s.jpg|left|200px]]
-
{{Structure
+
<!--
-
|PDB= 2z2s |SIZE=350|CAPTION= <scene name='initialview01'>2z2s</scene>, resolution 2.7&Aring;
+
The line below this paragraph, containing "STRUCTURE_2z2s", creates the "Structure Box" on the page.
-
|SITE= <scene name='pdbsite=AC1:Zn+Binding+Site+For+Residue+B+1'>AC1</scene>, <scene name='pdbsite=AC2:Zn+Binding+Site+For+Residue+H+1'>AC2</scene>, <scene name='pdbsite=AC3:Zn+Binding+Site+For+Residue+D+1'>AC3</scene>, <scene name='pdbsite=AC4:Zn+Binding+Site+For+Residue+F+1'>AC4</scene>, <scene name='pdbsite=AC5:So4+Binding+Site+For+Residue+E+1'>AC5</scene> and <scene name='pdbsite=AC6:So4+Binding+Site+For+Residue+G+2'>AC6</scene>
+
You may change the PDB parameter (which sets the PDB file loaded into the applet)
-
|LIGAND= <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene>
+
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-
|ACTIVITY=
+
or leave the SCENE parameter empty for the default display.
-
|GENE= rpoE ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1063 Rhodobacter sphaeroides]), chrR ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1063 Rhodobacter sphaeroides])
+
-->
-
|DOMAIN=
+
{{STRUCTURE_2z2s| PDB=2z2s | SCENE= }}
-
|RELATEDENTRY=[[2q1z|2Q1Z]]
+
-
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2z2s FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2z2s OCA], [http://www.ebi.ac.uk/pdbsum/2z2s PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2z2s RCSB]</span>
+
-
}}
+
'''Crystal Structure of Rhodobacter sphaeroides SigE in complex with the anti-sigma ChrR'''
'''Crystal Structure of Rhodobacter sphaeroides SigE in complex with the anti-sigma ChrR'''
Line 27: Line 24:
[[Category: Campbell, E A.]]
[[Category: Campbell, E A.]]
[[Category: Darst, S A.]]
[[Category: Darst, S A.]]
-
[[Category: activator]]
+
[[Category: Activator]]
-
[[Category: anti-sigma factor]]
+
[[Category: Anti-sigma factor]]
-
[[Category: cupin fold]]
+
[[Category: Cupin fold]]
-
[[Category: dna-binding]]
+
[[Category: Dna-binding]]
-
[[Category: ecf sigma factor]]
+
[[Category: Ecf sigma factor]]
-
[[Category: metal-binding]]
+
[[Category: Metal-binding]]
-
[[Category: transcription]]
+
[[Category: Transcription]]
-
[[Category: transcription regulation]]
+
[[Category: Transcription regulation]]
-
[[Category: zinc]]
+
[[Category: Zinc]]
-
[[Category: zinc binding transcription factor]]
+
[[Category: Zinc binding transcription factor]]
-
 
+
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun May 4 19:52:55 2008''
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 05:17:52 2008''
+

Revision as of 16:52, 4 May 2008

Image:2z2s.jpg

Template:STRUCTURE 2z2s

Crystal Structure of Rhodobacter sphaeroides SigE in complex with the anti-sigma ChrR


Overview

A transcriptional response to singlet oxygen in Rhodobacter sphaeroides is controlled by the group IV sigma factor sigma(E) and its cognate anti-sigma ChrR. Crystal structures of the sigma(E)/ChrR complex reveal a modular, two-domain architecture for ChrR. The ChrR N-terminal anti-sigma domain (ASD) binds a Zn(2+) ion, contacts sigma(E), and is sufficient to inhibit sigma(E)-dependent transcription. The ChrR C-terminal domain adopts a cupin fold, can coordinate an additional Zn(2+), and is required for the transcriptional response to singlet oxygen. Structure-based sequence analyses predict that the ASD defines a common structural fold among predicted group IV anti-sigmas. These ASDs are fused to diverse C-terminal domains that are likely involved in responding to specific environmental signals that control the activity of their cognate sigma factor.

About this Structure

2Z2S is a Protein complex structure of sequences from Rhodobacter sphaeroides. Full crystallographic information is available from OCA.

Reference

A conserved structural module regulates transcriptional responses to diverse stress signals in bacteria., Campbell EA, Greenwell R, Anthony JR, Wang S, Lim L, Das K, Sofia HJ, Donohue TJ, Darst SA, Mol Cell. 2007 Sep 7;27(5):793-805. PMID:17803943 Page seeded by OCA on Sun May 4 19:52:55 2008

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/2z2s"
Personal tools