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3f2u
From Proteopedia
(Difference between revisions)
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==Crystal structure of human chromobox homolog 1 (CBX1)== | ==Crystal structure of human chromobox homolog 1 (CBX1)== | ||
| - | <StructureSection load='3f2u' size='340' side='right' caption='[[3f2u]], [[Resolution|resolution]] 1.80Å' scene=''> | + | <StructureSection load='3f2u' size='340' side='right'caption='[[3f2u]], [[Resolution|resolution]] 1.80Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[3f2u]] is a 1 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[3f2u]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3F2U OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3F2U FirstGlance]. <br> |
| - | </td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">CBX1, CBX ([ | + | </td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">CBX1, CBX ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3f2u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3f2u OCA], [https://pdbe.org/3f2u PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3f2u RCSB], [https://www.ebi.ac.uk/pdbsum/3f2u PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3f2u ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [[ | + | [[https://www.uniprot.org/uniprot/CBX1_HUMAN CBX1_HUMAN]] Component of heterochromatin. Recognizes and binds histone H3 tails methylated at 'Lys-9', leading to epigenetic repression. Interaction with lamin B receptor (LBR) can contribute to the association of the heterochromatin with the inner nuclear membrane. |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Human]] | [[Category: Human]] | ||
| + | [[Category: Large Structures]] | ||
[[Category: Amaya, M F]] | [[Category: Amaya, M F]] | ||
[[Category: Arrowsmith, C H]] | [[Category: Arrowsmith, C H]] | ||
Revision as of 09:22, 23 February 2022
Crystal structure of human chromobox homolog 1 (CBX1)
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Categories: Human | Large Structures | Amaya, M F | Arrowsmith, C H | Botchkarev, A | Bountra, C | Edwards, A M | Kozieradzki, I | Loppnau, P | Min, J | Ouyang, H | Ravichandran, M | Structural genomic | Tempel, W | Weigelt, J | Wernimont, A K | Cbx1 | Centromere | Human chromobox homolog 1 | Nucleus | Phosphoprotein | Protein binding | Sgc
