3ezz

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==Crystal Structure of human MKP-2==
==Crystal Structure of human MKP-2==
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<StructureSection load='3ezz' size='340' side='right' caption='[[3ezz]], [[Resolution|resolution]] 2.90&Aring;' scene=''>
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<StructureSection load='3ezz' size='340' side='right'caption='[[3ezz]], [[Resolution|resolution]] 2.90&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3ezz]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3EZZ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3EZZ FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3ezz]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3EZZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3EZZ FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">DUSP4, MKP2, VH2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">DUSP4, MKP2, VH2 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ezz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ezz OCA], [http://pdbe.org/3ezz PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3ezz RCSB], [http://www.ebi.ac.uk/pdbsum/3ezz PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3ezz ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ezz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ezz OCA], [https://pdbe.org/3ezz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ezz RCSB], [https://www.ebi.ac.uk/pdbsum/3ezz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ezz ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/DUS4_HUMAN DUS4_HUMAN]] Regulates mitogenic signal transduction by dephosphorylating both Thr and Tyr residues on MAP kinases ERK1 and ERK2.
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[[https://www.uniprot.org/uniprot/DUS4_HUMAN DUS4_HUMAN]] Regulates mitogenic signal transduction by dephosphorylating both Thr and Tyr residues on MAP kinases ERK1 and ERK2.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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</StructureSection>
</StructureSection>
[[Category: Human]]
[[Category: Human]]
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[[Category: Large Structures]]
[[Category: Jeong, D G]]
[[Category: Jeong, D G]]
[[Category: Jung, S K]]
[[Category: Jung, S K]]

Revision as of 07:37, 10 November 2021

Crystal Structure of human MKP-2

PDB ID 3ezz

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