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6imf

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'''Unreleased structure'''
 
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The entry 6imf is ON HOLD until Paper Publication
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==Crystal structure of TOXIN/ANTITOXIN complex==
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<StructureSection load='6imf' size='340' side='right' caption='[[6imf]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
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Authors: Shioi, N., Tadokoro, T., Shioi, S., Hu, Y., Kurahara, L.H., Okabe, Y., Matsubara, H., Kita, S., Ose, T., Kuroki, K., Maenaka, K., Terada, S.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[6imf]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Protobothrops_flavoviridis Protobothrops flavoviridis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6IMF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6IMF FirstGlance]. <br>
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Description: Crystal structure of TOXIN/ANTITOXIN complex
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MES:2-(N-MORPHOLINO)-ETHANESULFONIC+ACID'>MES</scene></td></tr>
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[[Category: Unreleased Structures]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6imf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6imf OCA], [http://pdbe.org/6imf PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6imf RCSB], [http://www.ebi.ac.uk/pdbsum/6imf PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6imf ProSAT]</span></td></tr>
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[[Category: Terada, S]]
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</table>
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[[Category: Okabe, Y]]
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== Function ==
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[[Category: Shioi, N]]
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[[http://www.uniprot.org/uniprot/CRVP_PROFL CRVP_PROFL]] Blocks contraction of smooth muscle elicited by high potassium-induced depolarization (PubMed:12047379). May target voltage-gated calcium channels (Cav) on smooth muscle.<ref>PMID:12047379</ref> [[http://www.uniprot.org/uniprot/MSMB2_PROFL MSMB2_PROFL]] May serve as a self-defense protein against the toxic effects of the snake venom during accidental envenomation. Does not show inhibitory activity towards brevilysin H6.
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[[Category: Kurahara, L.H]]
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== References ==
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[[Category: Ose, T]]
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<references/>
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[[Category: Matsubara, H]]
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__TOC__
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</StructureSection>
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[[Category: Protobothrops flavoviridis]]
[[Category: Hu, Y]]
[[Category: Hu, Y]]
[[Category: Kita, S]]
[[Category: Kita, S]]
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[[Category: Tadokoro, T]]
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[[Category: Kurahara, L H]]
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[[Category: Kuroki, K]]
[[Category: Maenaka, K]]
[[Category: Maenaka, K]]
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[[Category: Kuroki, K]]
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[[Category: Matsubara, H]]
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[[Category: Okabe, Y]]
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[[Category: Ose, T]]
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[[Category: Shioi, N]]
[[Category: Shioi, S]]
[[Category: Shioi, S]]
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[[Category: Tadokoro, T]]
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[[Category: Terada, S]]
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[[Category: Antitoxin]]
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[[Category: Complex]]
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[[Category: Toxin]]
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[[Category: Toxin-antitoxin complex]]

Revision as of 06:55, 12 December 2018

Crystal structure of TOXIN/ANTITOXIN complex

6imf, resolution 2.30Å

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