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3fww
From Proteopedia
(Difference between revisions)
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==The crystal structure of the bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase from Yersinia pestis CO92== | ==The crystal structure of the bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase from Yersinia pestis CO92== | ||
| - | <StructureSection load='3fww' size='340' side='right' caption='[[3fww]], [[Resolution|resolution]] 2.50Å' scene=''> | + | <StructureSection load='3fww' size='340' side='right'caption='[[3fww]], [[Resolution|resolution]] 2.50Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[3fww]] is a 1 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[3fww]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Yerpp Yerpp]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3FWW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3FWW FirstGlance]. <br> |
| - | </td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">gi: 16124227, glmU, YPDSF_3916 ([ | + | </td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">gi: 16124227, glmU, YPDSF_3916 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=386656 YERPP])</td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3fww FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3fww OCA], [https://pdbe.org/3fww PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3fww RCSB], [https://www.ebi.ac.uk/pdbsum/3fww PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3fww ProSAT], [https://www.topsan.org/Proteins/CSGID/3fww TOPSAN]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [[ | + | [[https://www.uniprot.org/uniprot/GLMU_YERPP GLMU_YERPP]] Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.[HAMAP-Rule:MF_01631] |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3fww ConSurf]. | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3fww ConSurf]. | ||
<div style="clear:both"></div> | <div style="clear:both"></div> | ||
| + | |||
| + | ==See Also== | ||
| + | *[[N-acetylglucosamine-1-phosphate uridyltransferase|N-acetylglucosamine-1-phosphate uridyltransferase]] | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
[[Category: Yerpp]] | [[Category: Yerpp]] | ||
[[Category: Anderson, W]] | [[Category: Anderson, W]] | ||
Revision as of 08:13, 2 March 2022
The crystal structure of the bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase from Yersinia pestis CO92
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Categories: Large Structures | Yerpp | Anderson, W | Structural genomic | Gu, M | Joachimiak, A | Stam, J | Zhang, R | Acyltransferase | Cell shape | Cell wall biogenesis/degradation | Csgid | Magnesium | Metal-binding | Multifunctional enzyme | N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase | Nucleotidyltransferase | Peptidoglycan synthesis | Transferase
