Journal:Acta Cryst D:S2059798318017047
From Proteopedia
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<b>Molecular Tour</b><br> | <b>Molecular Tour</b><br> | ||
| + | The crystal structure of the N-acetylglucosamine-2-epimerase from Nostoc sp. KVJ10 (nAGE10) was obtained at a resolution of 1.7ֳ…. The nAGE10 monomer is folds as a (־±/ ־±)6-barrel in a manner similar to the previously published AGE structures. It is deposited in the PDB as 6F04. | ||
| + | The previously reported dimer organization, which involved the ג€backsג€ of the monomers, could not be found within the nAGE10 crystal. However, a ג€front-to-frontג€ dimer generated by symmetry is present in all AGE structures with better parameters than the back-to-back organization. | ||
| + | The new AGE dimer places the putative ATP binding site(s) at the interface between the monomers with consequences regarding its role in AGE activity. | ||
<b>References</b><br> | <b>References</b><br> | ||
Revision as of 09:40, 5 December 2018
http://proteopedia.org/w/Journal:Acta_Cryst_D:S2059798318017047
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