Beta-lactamase
From Proteopedia
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'''Beta-lactamase''' (Blac) are enzymes which make bacteria resistant to β-lactam antibiotics by breaking their β-lactam ring. Blac are classified according to their resistance targets.<br /> | '''Beta-lactamase''' (Blac) are enzymes which make bacteria resistant to β-lactam antibiotics by breaking their β-lactam ring. Blac are classified according to their resistance targets.<br /> | ||
| - | *Class A are broad-spectrum<br /> | + | *Class A are broad-spectrum. See also [[TEM1 Class Antibiotic Resistance Proteins]].<br /> |
*Class B are metalloenzymes. <br /> | *Class B are metalloenzymes. <br /> | ||
*Class C are cephalosporinases. See also [[Class C beta-lactamase]].<br /> | *Class C are cephalosporinases. See also [[Class C beta-lactamase]].<br /> | ||
Revision as of 10:22, 10 February 2019
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3D Structures of Beta-lactamase
Updated on 10-February-2019
References
- ↑ King D, Strynadka N. Crystal structure of New Delhi metallo-beta-lactamase reveals molecular basis for antibiotic resistance. Protein Sci. 2011 Sep;20(9):1484-91. doi: 10.1002/pro.697. Epub 2011 Aug, 2. PMID:21774017 doi:10.1002/pro.697
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