This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
3gee
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
==Crystal structure of MnmE from Chlorobium tepidum in complex with GDP and FOLINIC ACID== | ==Crystal structure of MnmE from Chlorobium tepidum in complex with GDP and FOLINIC ACID== | ||
| - | <StructureSection load='3gee' size='340' side='right' caption='[[3gee]], [[Resolution|resolution]] 2.95Å' scene=''> | + | <StructureSection load='3gee' size='340' side='right'caption='[[3gee]], [[Resolution|resolution]] 2.95Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[3gee]] is a 1 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[3gee]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Atcc_49652 Atcc 49652]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3GEE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3GEE FirstGlance]. <br> |
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FON:N-{[4-({[(6R)-2-AMINO-5-FORMYL-4-OXO-1,4,5,6,7,8-HEXAHYDROPTERIDIN-6-YL]METHYL}AMINO)PHENYL]CARBONYL}-L-GLUTAMIC+ACID'>FON</scene>, <scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene></td></tr> | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FON:N-{[4-({[(6R)-2-AMINO-5-FORMYL-4-OXO-1,4,5,6,7,8-HEXAHYDROPTERIDIN-6-YL]METHYL}AMINO)PHENYL]CARBONYL}-L-GLUTAMIC+ACID'>FON</scene>, <scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene></td></tr> |
| - | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1rfl|1rfl]], [[1xzp|1xzp]], [[1xzq|1xzq]], [[2gja|2gja]], [[2gj8|2gj8]], [[2gj9|2gj9]], [[3cp2|3cp2]], [[3cp8|3cp8]], [[3geh|3geh]], [[3gei|3gei]]</td></tr> | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1rfl|1rfl]], [[1xzp|1xzp]], [[1xzq|1xzq]], [[2gja|2gja]], [[2gj8|2gj8]], [[2gj9|2gj9]], [[3cp2|3cp2]], [[3cp8|3cp8]], [[3geh|3geh]], [[3gei|3gei]]</div></td></tr> |
| - | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">mnmE, CT2084, thdF, trmE ([ | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">mnmE, CT2084, thdF, trmE ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1097 ATCC 49652])</td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3gee FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3gee OCA], [https://pdbe.org/3gee PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3gee RCSB], [https://www.ebi.ac.uk/pdbsum/3gee PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3gee ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [[ | + | [[https://www.uniprot.org/uniprot/MNME_CHLTE MNME_CHLTE]] Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.[HAMAP-Rule:MF_00379] |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
| Line 35: | Line 35: | ||
</StructureSection> | </StructureSection> | ||
[[Category: Atcc 49652]] | [[Category: Atcc 49652]] | ||
| + | [[Category: Large Structures]] | ||
[[Category: Meyer, S]] | [[Category: Meyer, S]] | ||
[[Category: Wittinghofer, A]] | [[Category: Wittinghofer, A]] | ||
Revision as of 08:02, 9 March 2022
Crystal structure of MnmE from Chlorobium tepidum in complex with GDP and FOLINIC ACID
| |||||||||||
Categories: Atcc 49652 | Large Structures | Meyer, S | Wittinghofer, A | Cytoplasm | G protein | Gtp-binding | Gtpase | Hydrolase | Magnesium | Metal-binding | Nucleotide-binding | Potassium | Trna modification | Trna processing | U34

