This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
Sandbox Reserved 1474
From Proteopedia
(Difference between revisions)
| Line 49: | Line 49: | ||
<ref name="Aromatic-Aromatic Interaction">PMID: 3892686</ref> | <ref name="Aromatic-Aromatic Interaction">PMID: 3892686</ref> | ||
<ref name="Generation 2000">DOI: 10.1016/S1567-5769(00)00019-9</ref> | <ref name="Generation 2000">DOI: 10.1016/S1567-5769(00)00019-9</ref> | ||
| + | <ref name="designing immunotherapies to thwart drug abuse">PMID: 19592672</ref> | ||
| + | |||
| + | |||
<references/> | <references/> | ||
Revision as of 05:31, 8 December 2018
Contents |
Immunotherapy for treating Methamphetamine Abuse
Introduction
Two major approaches to developing drug-specific immunotherapies: active and passive immunization
Antibody pharmacokinetics, pharmacodynamics and metabolism of therapeutic and diagnostic antibodies
Generation of anti-(+)methamphetamine antibodies during active immunization of rats
Function
Disease
Relevance
Structural highlights
Aromatic-Aromatic Interaction: A Mechanism of Protein Structure Stabilization
| |||||||||
| scFv6H4 in complex with amphetamine | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Ligands: | , | ||||||||
| Gene: | IgG (LK3 transgenic mice) | ||||||||
| Activity: | , | ||||||||
| Related: | 3gkz, 4laq, 4las | ||||||||
| |||||||||
| Resources: | FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT | ||||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||||
This is a sample scene created with SAT to by Group, and another to make of the protein. You can make your own scenes on SAT starting from scratch or loading and editing one of these sample scenes.
</StructureSection>
References
- ↑ Burley SK, Petsko GA. Aromatic-aromatic interaction: a mechanism of protein structure stabilization. Science. 1985 Jul 5;229(4708):23-8. PMID:3892686
- ↑ doi: https://dx.doi.org/10.1016/S1567-5769(00)00019-9
- ↑ Peterson EC, Owens SM. Designing immunotherapies to thwart drug abuse. Mol Interv. 2009 Jun;9(3):119-24. doi: 10.1124/mi.9.3.5. PMID:19592672 doi:http://dx.doi.org/10.1124/mi.9.3.5
