3of3

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Current revision (09:37, 6 September 2023) (edit) (undo)
 
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==Crystal structure of PNP with an inhibitor DADME_immH from Vibrio cholerae==
==Crystal structure of PNP with an inhibitor DADME_immH from Vibrio cholerae==
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<StructureSection load='3of3' size='340' side='right' caption='[[3of3]], [[Resolution|resolution]] 1.83&Aring;' scene=''>
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<StructureSection load='3of3' size='340' side='right'caption='[[3of3]], [[Resolution|resolution]] 1.83&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3of3]] is a 12 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillo_virgola_del_koch"_trevisan_1884 "bacillo virgola del koch" trevisan 1884]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3OF3 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3OF3 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3of3]] is a 12 chain structure with sequence from [https://en.wikipedia.org/wiki/Vibrio_cholerae Vibrio cholerae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3OF3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3OF3 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=DIH:3-HYDROXY-4-HYDROXYMETHYL-1-(4-OXO-4,4A,5,7A-TETRAHYDRO-3H-PYRROLO[3,2-D]PYRIMIDIN-7-YLMETHYL)-PYRROLIDINIUM'>DIH</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.83&#8491;</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">deoD, deoD1, VC_2347 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=666 "Bacillo virgola del Koch" Trevisan 1884])</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DIH:3-HYDROXY-4-HYDROXYMETHYL-1-(4-OXO-4,4A,5,7A-TETRAHYDRO-3H-PYRROLO[3,2-D]PYRIMIDIN-7-YLMETHYL)-PYRROLIDINIUM'>DIH</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Purine-nucleoside_phosphorylase Purine-nucleoside phosphorylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.2.1 2.4.2.1] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3of3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3of3 OCA], [https://pdbe.org/3of3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3of3 RCSB], [https://www.ebi.ac.uk/pdbsum/3of3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3of3 ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3of3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3of3 OCA], [http://pdbe.org/3of3 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3of3 RCSB], [http://www.ebi.ac.uk/pdbsum/3of3 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3of3 ProSAT]</span></td></tr>
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</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/DEOD1_VIBCH DEOD1_VIBCH]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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==See Also==
==See Also==
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*[[Purine nucleoside phosphorylase|Purine nucleoside phosphorylase]]
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*[[Purine nucleoside phosphorylase 3D structures|Purine nucleoside phosphorylase 3D structures]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Bacillo virgola del koch trevisan 1884]]
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[[Category: Large Structures]]
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[[Category: Purine-nucleoside phosphorylase]]
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[[Category: Vibrio cholerae]]
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[[Category: Almo, S C]]
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[[Category: Almo SC]]
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[[Category: Burley, S K]]
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[[Category: Burley SK]]
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[[Category: Kim, J]]
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[[Category: Kim J]]
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[[Category: Structural genomic]]
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[[Category: Ramagopal UA]]
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[[Category: Ramagopal, U A]]
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[[Category: NYSGXRC, New York SGX Research Center for Structural Genomics]]
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[[Category: Phophoryl transferase]]
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[[Category: Phosphate]]
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[[Category: PSI, Protein structure initiative]]
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[[Category: Purine nucleoside]]
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[[Category: Transferase]]
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Current revision

Crystal structure of PNP with an inhibitor DADME_immH from Vibrio cholerae

PDB ID 3of3

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