3hmh

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==Crystal structure of the second bromodomain of human TBP-associated factor RNA polymerase 1-like (TAF1L)==
==Crystal structure of the second bromodomain of human TBP-associated factor RNA polymerase 1-like (TAF1L)==
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<StructureSection load='3hmh' size='340' side='right' caption='[[3hmh]], [[Resolution|resolution]] 2.05&Aring;' scene=''>
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<StructureSection load='3hmh' size='340' side='right'caption='[[3hmh]], [[Resolution|resolution]] 2.05&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3hmh]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HMH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3HMH FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3hmh]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HMH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3HMH FirstGlance]. <br>
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</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3hme|3hme]], [[3hmf|3hmf]]</td></tr>
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</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3hme|3hme]], [[3hmf|3hmf]]</div></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">TAF1L ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">TAF1L ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3hmh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3hmh OCA], [http://pdbe.org/3hmh PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3hmh RCSB], [http://www.ebi.ac.uk/pdbsum/3hmh PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3hmh ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3hmh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3hmh OCA], [https://pdbe.org/3hmh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3hmh RCSB], [https://www.ebi.ac.uk/pdbsum/3hmh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3hmh ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/TAF1L_HUMAN TAF1L_HUMAN]] May act as a functional substitute for TAF1/TAFII250 during male meiosis, when sex chromosomes are transcriptionally silenced.<ref>PMID:12217962</ref>
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[[https://www.uniprot.org/uniprot/TAF1L_HUMAN TAF1L_HUMAN]] May act as a functional substitute for TAF1/TAFII250 during male meiosis, when sex chromosomes are transcriptionally silenced.<ref>PMID:12217962</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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</StructureSection>
</StructureSection>
[[Category: Human]]
[[Category: Human]]
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[[Category: Large Structures]]
[[Category: Arrowsmith, C H]]
[[Category: Arrowsmith, C H]]
[[Category: Bountra, C]]
[[Category: Bountra, C]]

Revision as of 12:52, 23 March 2022

Crystal structure of the second bromodomain of human TBP-associated factor RNA polymerase 1-like (TAF1L)

PDB ID 3hmh

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