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3hkc

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==Tubulin-ABT751: RB3 stathmin-like domain complex==
==Tubulin-ABT751: RB3 stathmin-like domain complex==
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<StructureSection load='3hkc' size='340' side='right' caption='[[3hkc]], [[Resolution|resolution]] 3.80&Aring;' scene=''>
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<StructureSection load='3hkc' size='340' side='right'caption='[[3hkc]], [[Resolution|resolution]] 3.80&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3hkc]] is a 5 chain structure with sequence from [http://en.wikipedia.org/wiki/Buffalo_rat Buffalo rat] and [http://en.wikipedia.org/wiki/Ovis_aries Ovis aries]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HKC OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3HKC FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3hkc]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Buffalo_rat Buffalo rat] and [https://en.wikipedia.org/wiki/Ovis_aries Ovis aries]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HKC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3HKC FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=E70:N-{2-[(4-HYDROXYPHENYL)AMINO]PYRIDIN-3-YL}-4-METHOXYBENZENESULFONAMIDE'>E70</scene>, <scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene>, <scene name='pdbligand=GTP:GUANOSINE-5-TRIPHOSPHATE'>GTP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=E70:N-{2-[(4-HYDROXYPHENYL)AMINO]PYRIDIN-3-YL}-4-METHOXYBENZENESULFONAMIDE'>E70</scene>, <scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene>, <scene name='pdbligand=GTP:GUANOSINE-5-TRIPHOSPHATE'>GTP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1sa0|1sa0]], [[1sa1|1sa1]], [[3hkb|3hkb]], [[3hkd|3hkd]], [[3hke|3hke]]</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1sa0|1sa0]], [[1sa1|1sa1]], [[3hkb|3hkb]], [[3hkd|3hkd]], [[3hke|3hke]]</div></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">STMN4 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10116 Buffalo rat])</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">STMN4 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10116 Buffalo rat])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3hkc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3hkc OCA], [http://pdbe.org/3hkc PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3hkc RCSB], [http://www.ebi.ac.uk/pdbsum/3hkc PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3hkc ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3hkc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3hkc OCA], [https://pdbe.org/3hkc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3hkc RCSB], [https://www.ebi.ac.uk/pdbsum/3hkc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3hkc ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/STMN4_RAT STMN4_RAT]] Exhibits microtubule-destabilizing activity.<ref>PMID:15039434</ref> <ref>PMID:12111843</ref> <ref>PMID:15014504</ref>
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[[https://www.uniprot.org/uniprot/STMN4_RAT STMN4_RAT]] Exhibits microtubule-destabilizing activity.<ref>PMID:15039434</ref> <ref>PMID:12111843</ref> <ref>PMID:15014504</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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==See Also==
==See Also==
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*[[Stathmin|Stathmin]]
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*[[Stathmin-4 3D structures|Stathmin-4 3D structures]]
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*[[Tubulin|Tubulin]]
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*[[Tubulin 3D Structures|Tubulin 3D Structures]]
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*[[User:Alisa Cario|User:Alisa Cario]]
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== References ==
== References ==
<references/>
<references/>
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</StructureSection>
</StructureSection>
[[Category: Buffalo rat]]
[[Category: Buffalo rat]]
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[[Category: Large Structures]]
[[Category: Ovis aries]]
[[Category: Ovis aries]]
[[Category: Dorleans, A]]
[[Category: Dorleans, A]]

Revision as of 12:50, 23 March 2022

Tubulin-ABT751: RB3 stathmin-like domain complex

PDB ID 3hkc

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