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3hks

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==Crystal structure of eukaryotic translation initiation factor eIF-5A2 from Arabidopsis thaliana==
==Crystal structure of eukaryotic translation initiation factor eIF-5A2 from Arabidopsis thaliana==
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<StructureSection load='3hks' size='340' side='right' caption='[[3hks]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
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<StructureSection load='3hks' size='340' side='right'caption='[[3hks]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3hks]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Arath Arath]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HKS OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3HKS FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3hks]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Arath Arath]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HKS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3HKS FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">At1G26630.1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=3702 ARATH])</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">At1G26630.1 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=3702 ARATH])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3hks FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3hks OCA], [http://pdbe.org/3hks PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3hks RCSB], [http://www.ebi.ac.uk/pdbsum/3hks PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3hks ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3hks FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3hks OCA], [https://pdbe.org/3hks PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3hks RCSB], [https://www.ebi.ac.uk/pdbsum/3hks PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3hks ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/IF5A2_ARATH IF5A2_ARATH]] The precise role of eIF-5A in protein biosynthesis is not known but it may function as a bimodular protein capable of binding to both RNA and proteins. Regulates cytokinin-mediated root protoxylem specification and represses secifically the expression of AHP6. Regulates the induction of programmed cell death caused by infection with virulent pathogen.<ref>PMID:17513484</ref> <ref>PMID:18633122</ref> <ref>PMID:24163315</ref>
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[[https://www.uniprot.org/uniprot/IF5A2_ARATH IF5A2_ARATH]] The precise role of eIF-5A in protein biosynthesis is not known but it may function as a bimodular protein capable of binding to both RNA and proteins. Regulates cytokinin-mediated root protoxylem specification and represses secifically the expression of AHP6. Regulates the induction of programmed cell death caused by infection with virulent pathogen.<ref>PMID:17513484</ref> <ref>PMID:18633122</ref> <ref>PMID:24163315</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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==See Also==
==See Also==
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*[[Eukaryotic initiation factor|Eukaryotic initiation factor]]
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*[[Eukaryotic initiation factor 3D structures|Eukaryotic initiation factor 3D structures]]
== References ==
== References ==
<references/>
<references/>
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</StructureSection>
</StructureSection>
[[Category: Arath]]
[[Category: Arath]]
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[[Category: Large Structures]]
[[Category: Chen, Y X]]
[[Category: Chen, Y X]]
[[Category: He, Y X]]
[[Category: He, Y X]]

Revision as of 12:50, 23 March 2022

Crystal structure of eukaryotic translation initiation factor eIF-5A2 from Arabidopsis thaliana

PDB ID 3hks

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