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6f6z
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==Mouse Thymidylate Synthase Cocrystallized with N(4)OHdCMP and Soaked in Methylenetetrahydrofolate== | |
| - | + | <StructureSection load='6f6z' size='340' side='right' caption='[[6f6z]], [[Resolution|resolution]] 2.13Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[6f6z]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6F6Z OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6F6Z FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NOH:2-DEOXY-N-HYDROXYCYTIDINE+5-(DIHYDROGEN+PHOSPHATE)'>NOH</scene>, <scene name='pdbligand=TGQ:(2~{S})-2-[[4-[[(6~{R})-2-azanyl-4-oxidanylidene-5,6,7,8-tetrahydro-1~{H}-pteridin-6-yl]methyl-methyl-amino]phenyl]carbonylamino]pentanedioic+acid'>TGQ</scene></td></tr> | |
| - | [[ | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Thymidylate_synthase Thymidylate synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.1.45 2.1.1.45] </span></td></tr> |
| - | [[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6f6z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6f6z OCA], [http://pdbe.org/6f6z PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6f6z RCSB], [http://www.ebi.ac.uk/pdbsum/6f6z PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6f6z ProSAT]</span></td></tr> |
| - | [[ | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/TYSY_MOUSE TYSY_MOUSE]] Contributes to the de novo mitochondrial thymidylate biosynthesis pathway (By similarity). | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Thymidylate synthase]] | ||
[[Category: Jarmula, A]] | [[Category: Jarmula, A]] | ||
[[Category: Maj, P]] | [[Category: Maj, P]] | ||
| + | [[Category: Rode, W]] | ||
| + | [[Category: Wilk, P]] | ||
| + | [[Category: Cofactor]] | ||
| + | [[Category: Enzyme]] | ||
| + | [[Category: Inhibitor]] | ||
| + | [[Category: Transferase]] | ||
Revision as of 08:17, 30 January 2019
Mouse Thymidylate Synthase Cocrystallized with N(4)OHdCMP and Soaked in Methylenetetrahydrofolate
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Categories: Thymidylate synthase | Jarmula, A | Maj, P | Rode, W | Wilk, P | Cofactor | Enzyme | Inhibitor | Transferase
