6q6c

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m (Protected "6q6c" [edit=sysop:move=sysop])
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'''Unreleased structure'''
 
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The entry 6q6c is ON HOLD until Paper Publication
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==Pore-modulating toxins exploit inherent slow inactivation to block K+ channels==
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<StructureSection load='6q6c' size='340' side='right'caption='[[6q6c]], [[Resolution|resolution]] 1.30&Aring;' scene=''>
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Authors: Karbat, I., Gueta, H., Fine, S., Szanto, T., Hamer-Rogotner, S., Dym, O., Frolow, F., Gordon, D., Panyi, G., Gurevitz, M., Reuveny, E.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[6q6c]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6Q6C OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6Q6C FirstGlance]. <br>
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Description: Pore-modulating toxins exploit inherent slow inactivation to block K+ channels
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=NO3:NITRATE+ION'>NO3</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
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[[Category: Unreleased Structures]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6q6c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6q6c OCA], [http://pdbe.org/6q6c PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6q6c RCSB], [http://www.ebi.ac.uk/pdbsum/6q6c PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6q6c ProSAT]</span></td></tr>
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[[Category: Reuveny, E]]
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/VKTS1_CONST VKTS1_CONST]] Blocks specifically voltage-activated potassium channels (Kv) of the Shaker family (IC(50)=1.33 nM).<ref>PMID:15833744</ref>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
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[[Category: Dym, O]]
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[[Category: Fine, S]]
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[[Category: Frolow, F]]
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[[Category: Gordon, D]]
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[[Category: Gueta, H]]
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[[Category: Gurevitz, M]]
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[[Category: Hamer-Rogotner, S]]
[[Category: Karbat, I]]
[[Category: Karbat, I]]
[[Category: Panyi, G]]
[[Category: Panyi, G]]
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[[Category: Hamer-Rogotner, S]]
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[[Category: Reuveny, E]]
[[Category: Szanto, T]]
[[Category: Szanto, T]]
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[[Category: Gurevitz, M]]
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[[Category: Toxin]]
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[[Category: Gordon, D]]
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[[Category: Frolow, F]]
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[[Category: Fine, S]]
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[[Category: Gueta, H]]
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[[Category: Dym, O]]
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Revision as of 06:06, 21 August 2019

Pore-modulating toxins exploit inherent slow inactivation to block K+ channels

PDB ID 6q6c

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