6i3s
From Proteopedia
(Difference between revisions)
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<StructureSection load='6i3s' size='340' side='right' caption='[[6i3s]], [[Resolution|resolution]] 1.77Å' scene=''> | <StructureSection load='6i3s' size='340' side='right' caption='[[6i3s]], [[Resolution|resolution]] 1.77Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[6i3s]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6I3S OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6I3S FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[6i3s]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6I3S OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6I3S FirstGlance]. <br> |
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=H28:(3~{S},3~{R},3~{a}~{S},6~{a}~{R})-6-chloranyl-3-(3-chloranyl-2-fluoranyl-phenyl)-1-(cyclopropylmethyl)spiro[1~{H}-indole-3,2-3~{a},6~{a}-dihydro-3~{H}-pyrrolo[3,4-b]pyrrole]-2,4-dione'>H28</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=H28:(3~{S},3~{R},3~{a}~{S},6~{a}~{R})-6-chloranyl-3-(3-chloranyl-2-fluoranyl-phenyl)-1-(cyclopropylmethyl)spiro[1~{H}-indole-3,2-3~{a},6~{a}-dihydro-3~{H}-pyrrolo[3,4-b]pyrrole]-2,4-dione'>H28</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | ||
| + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">MDM2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr> | ||
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/RING-type_E3_ubiquitin_transferase RING-type E3 ubiquitin transferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.3.2.27 2.3.2.27] </span></td></tr> | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/RING-type_E3_ubiquitin_transferase RING-type E3 ubiquitin transferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.3.2.27 2.3.2.27] </span></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6i3s FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6i3s OCA], [http://pdbe.org/6i3s PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6i3s RCSB], [http://www.ebi.ac.uk/pdbsum/6i3s PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6i3s ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6i3s FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6i3s OCA], [http://pdbe.org/6i3s PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6i3s RCSB], [http://www.ebi.ac.uk/pdbsum/6i3s PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6i3s ProSAT]</span></td></tr> | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| + | [[Category: Human]] | ||
[[Category: RING-type E3 ubiquitin transferase]] | [[Category: RING-type E3 ubiquitin transferase]] | ||
[[Category: Bader, G]] | [[Category: Bader, G]] | ||
Revision as of 08:45, 26 December 2018
Crystal structure of MDM2 in complex with compound 13.
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