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3iey
From Proteopedia
(Difference between revisions)
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==Crystal Structure of the functional Nanoarchaeum equitans tRNA splicing endonuclease== | ==Crystal Structure of the functional Nanoarchaeum equitans tRNA splicing endonuclease== | ||
| - | <StructureSection load='3iey' size='340' side='right' caption='[[3iey]], [[Resolution|resolution]] 2.11Å' scene=''> | + | <StructureSection load='3iey' size='340' side='right'caption='[[3iey]], [[Resolution|resolution]] 2.11Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[3iey]] is a 2 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[3iey]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/"nanoarchaeum_equitans"_huber_et_al._2002 "nanoarchaeum equitans" huber et al. 2002]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IEY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3IEY FirstGlance]. <br> |
| - | </td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3if0|3if0]]</td></tr> | + | </td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3if0|3if0]]</div></td></tr> |
| - | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">endA, NEQ205 ([ | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">endA, NEQ205 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=160232 "Nanoarchaeum equitans" Huber et al. 2002]), NEQ261 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=160232 "Nanoarchaeum equitans" Huber et al. 2002])</td></tr> |
| - | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/tRNA-intron_endonuclease tRNA-intron endonuclease], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.27.9 3.1.27.9] </span></td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3iey FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3iey OCA], [https://pdbe.org/3iey PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3iey RCSB], [https://www.ebi.ac.uk/pdbsum/3iey PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3iey ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [[ | + | [[https://www.uniprot.org/uniprot/ENDA_NANEQ ENDA_NANEQ]] Endonuclease that removes tRNA introns. Cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3' cyclic phosphate and 5'-OH termini. Recognizes a pseudosymmetric substrate in which 2 bulged loops of 3 bases are separated by a stem of 4 bp (By similarity). |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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==See Also== | ==See Also== | ||
| - | *[[Endonuclease|Endonuclease]] | + | *[[Endonuclease 3D structures|Endonuclease 3D structures]] |
== References == | == References == | ||
<references/> | <references/> | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Nanoarchaeum equitans huber et al. 2002]] | [[Category: Nanoarchaeum equitans huber et al. 2002]] | ||
| + | [[Category: Large Structures]] | ||
[[Category: TRNA-intron endonuclease]] | [[Category: TRNA-intron endonuclease]] | ||
[[Category: Li, H]] | [[Category: Li, H]] | ||
Revision as of 12:10, 13 October 2021
Crystal Structure of the functional Nanoarchaeum equitans tRNA splicing endonuclease
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