This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.


Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


5q01

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
-
'''Unreleased structure'''
 
-
The entry 5q01 is ON HOLD
+
==Human liver fructose-1,6-bisphosphatase 1 (fructose 1,6-bisphosphate 1-phosphatase, E.C.3.1.3.11) complexed with the allosteric inhibitor 1-(5-bromo-1,3-thiazol-2-yl)-3-[4-(4,5-dichloro-2-methylpyrazol-3-yl)oxyphenyl]sulfonylurea==
 +
<StructureSection load='5q01' size='340' side='right' caption='[[5q01]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
 +
== Structural highlights ==
 +
<table><tr><td colspan='2'>[[5q01]] is a 8 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5Q01 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5Q01 FirstGlance]. <br>
 +
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=95G:N-[(5-bromo-1,3-thiazol-2-yl)carbamoyl]-4-[(3,4-dichloro-1-methyl-1H-pyrazol-5-yl)oxy]benzene-1-sulfonamide'>95G</scene></td></tr>
 +
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Fructose-bisphosphatase Fructose-bisphosphatase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.3.11 3.1.3.11] </span></td></tr>
 +
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5q01 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5q01 OCA], [http://pdbe.org/5q01 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5q01 RCSB], [http://www.ebi.ac.uk/pdbsum/5q01 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5q01 ProSAT]</span></td></tr>
 +
</table>
-
Authors: Ruf, A., Joseph, C., Alker, A., Banner, D., Tetaz, T., Benz, J., Kuhn, B., Rudolph, M., Yang, H., Shao, C., Burley, S.K.
+
==See Also==
-
 
+
*[[Bile acid receptor|Bile acid receptor]]
-
Description: Human liver fructose-1,6-bisphosphatase 1 (fructose 1,6-bisphosphate 1-phosphatase, E.C.3.1.3.11) complexed with the allosteric inhibitor 1-(5-bromo-1,3-thiazol-2-yl)-3-[4-(4,5-dichloro-2-methylpyrazol-3-yl)oxyphenyl]sulfonylurea
+
__TOC__
-
[[Category: Unreleased Structures]]
+
</StructureSection>
 +
[[Category: Fructose-bisphosphatase]]
 +
[[Category: Alker, A]]
 +
[[Category: Banner, D]]
 +
[[Category: Benz, J]]
 +
[[Category: Burley, S K]]
 +
[[Category: Joseph, C]]
 +
[[Category: Kuhn, B]]
[[Category: Rudolph, M]]
[[Category: Rudolph, M]]
[[Category: Ruf, A]]
[[Category: Ruf, A]]
-
[[Category: Burley, S.K]]
+
[[Category: Shao, C]]
 +
[[Category: Tetaz, T]]
[[Category: Yang, H]]
[[Category: Yang, H]]
-
[[Category: Joseph, C]]
+
[[Category: D3r docking]]
-
[[Category: Tetaz, T]]
+
[[Category: Hydrolase-hydrolase inhibitor complex]]
-
[[Category: Shao, C]]
+
-
[[Category: Alker, A]]
+
-
[[Category: Benz, J]]
+
-
[[Category: Kuhn, B]]
+
-
[[Category: Banner, D]]
+

Revision as of 06:32, 9 January 2019

Human liver fructose-1,6-bisphosphatase 1 (fructose 1,6-bisphosphate 1-phosphatase, E.C.3.1.3.11) complexed with the allosteric inhibitor 1-(5-bromo-1,3-thiazol-2-yl)-3-[4-(4,5-dichloro-2-methylpyrazol-3-yl)oxyphenyl]sulfonylurea

5q01, resolution 2.60Å

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Personal tools