This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
3kn2
From Proteopedia
| Line 1: | Line 1: | ||
==HCV NS3 Protease Domain with ketoamide inhibitor== | ==HCV NS3 Protease Domain with ketoamide inhibitor== | ||
| - | <StructureSection load='3kn2' size='340' side='right' caption='[[3kn2]], [[Resolution|resolution]] 2.30Å' scene=''> | + | <StructureSection load='3kn2' size='340' side='right'caption='[[3kn2]], [[Resolution|resolution]] 2.30Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[3kn2]] is a 4 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[3kn2]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Hepatitis_c_virus_subtype_1a Hepatitis c virus subtype 1a]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KN2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3KN2 FirstGlance]. <br> |
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=M66:(1R,2S,5S)-3-{(2S)-2-(2,3-dihydro-1H-inden-2-yl)-2-[({(1S)-2,2-dimethyl-1-[(2-oxopiperidin-1-yl)methyl]propyl}carbamoyl)amino]acetyl}-6,6-dimethyl-N-{(1S)-1-[oxo(prop-2-en-1-ylamino)acetyl]butyl}-3-azabicyclo[3.1.0]hexane-2-carboxamide'>M66</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=M66:(1R,2S,5S)-3-{(2S)-2-(2,3-dihydro-1H-inden-2-yl)-2-[({(1S)-2,2-dimethyl-1-[(2-oxopiperidin-1-yl)methyl]propyl}carbamoyl)amino]acetyl}-6,6-dimethyl-N-{(1S)-1-[oxo(prop-2-en-1-ylamino)acetyl]butyl}-3-azabicyclo[3.1.0]hexane-2-carboxamide'>M66</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> |
| - | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">NS3 ([ | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">NS3 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=31646 Hepatitis C virus subtype 1a])</td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3kn2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3kn2 OCA], [https://pdbe.org/3kn2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3kn2 RCSB], [https://www.ebi.ac.uk/pdbsum/3kn2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3kn2 ProSAT]</span></td></tr> |
</table> | </table> | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
| Line 17: | Line 17: | ||
</div> | </div> | ||
<div class="pdbe-citations 3kn2" style="background-color:#fffaf0;"></div> | <div class="pdbe-citations 3kn2" style="background-color:#fffaf0;"></div> | ||
| + | |||
| + | ==See Also== | ||
| + | *[[Virus protease 3D structures|Virus protease 3D structures]] | ||
== References == | == References == | ||
<references/> | <references/> | ||
| Line 22: | Line 25: | ||
</StructureSection> | </StructureSection> | ||
[[Category: Hepatitis c virus subtype 1a]] | [[Category: Hepatitis c virus subtype 1a]] | ||
| + | [[Category: Large Structures]] | ||
[[Category: Bogen, S]] | [[Category: Bogen, S]] | ||
[[Category: Chen, K X]] | [[Category: Chen, K X]] | ||
Revision as of 12:27, 13 October 2021
HCV NS3 Protease Domain with ketoamide inhibitor
| |||||||||||
Categories: Hepatitis c virus subtype 1a | Large Structures | Bogen, S | Chen, K X | Nair, L G | Njoroge, G | Pinto, P | Prongay, A | Sannigrahi, M | Atp-binding | Capsid protein | Envelope protein | Helicase | Hepatitis c virus | Host membrane | Hydrolase | Ketoamide inhibitor | Membrane | Ns3 protease domain | Nucleotide-binding | Rna replication | Serine protease | Transmembrane | Virion
