Sandbox 1498
From Proteopedia
(Difference between revisions)
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3BPU is involved in the cell signalisation. It may play a role as a scaffolding protein at cell-cell junctions. It may also regulate acid-induced ASIC3<ref >http://www.rcsb.org/pdb/protein/Q9UHC3</ref> currents by modulating its expression at the cell surface through interacting with its PDZ domain. | 3BPU is involved in the cell signalisation. It may play a role as a scaffolding protein at cell-cell junctions. It may also regulate acid-induced ASIC3<ref >http://www.rcsb.org/pdb/protein/Q9UHC3</ref> currents by modulating its expression at the cell surface through interacting with its PDZ domain. | ||
| - | == Structure== | + | == Structure == |
| + | === Primary structure === | ||
| + | 3BPU is a one chain structure of 88 amino-acids. | ||
| + | |||
| + | === Secondary structure === | ||
| + | 3BPU structure is composed of 10% of helix (1 helix; 9 residues) and 40% of beta sheets (8 strands; 36 residues) | ||
| + | |||
| + | https://www.rcsb.org/3d-view/3BPU?preset=ligandInteraction&sele=ZN | ||
== References == | == References == | ||
<references/> | <references/> | ||
Revision as of 15:05, 29 December 2018
Contents |
3BPU
3BPU is a transferase found in Homo sapiens. It is the 3rd PDZ domain of human membrane associated guanylate kinase Q96QZ7, C677S and C709S double mutant. It is encoded by the MAGI1 gene. [1]
Function
3BPU is involved in the cell signalisation. It may play a role as a scaffolding protein at cell-cell junctions. It may also regulate acid-induced ASIC3[1] currents by modulating its expression at the cell surface through interacting with its PDZ domain.
Structure
Primary structure
3BPU is a one chain structure of 88 amino-acids.
Secondary structure
3BPU structure is composed of 10% of helix (1 helix; 9 residues) and 40% of beta sheets (8 strands; 36 residues)
https://www.rcsb.org/3d-view/3BPU?preset=ligandInteraction&sele=ZN
