Epithelial discoidin domain-containing receptor
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
| - | <StructureSection load=' | + | <StructureSection load='4bkj' size='340' side='right' caption='Caption for this structure' scene=''> |
| Line 27: | Line 27: | ||
[[5bvk]] – hDDR1 kinase domain 564-913 – human<br /> | [[5bvk]] – hDDR1 kinase domain 564-913 – human<br /> | ||
| - | [[3zos | + | [[3zos]], [[4bkj]] – hDDR1 kinase domain + cancer drug<br /> |
[[6few]] – hDDR1 kinase domain + alport syndrome drug<br /> | [[6few]] – hDDR1 kinase domain + alport syndrome drug<br /> | ||
[[6fex]], [[6fil]], [[6fim]], [[6fin]], [[6fio]], [[6fiq]] – hDDR1 kinase domain (mutant) + alport syndrome drug<br /> | [[6fex]], [[6fil]], [[6fim]], [[6fin]], [[6fio]], [[6fiq]] – hDDR1 kinase domain (mutant) + alport syndrome drug<br /> | ||
Revision as of 07:46, 31 December 2018
| |||||||||||
3D structures of epithelial discoidin domain-containing receptor 1
Updated on 31-December-2018
5bvk – hDDR1 kinase domain 564-913 – human
3zos, 4bkj – hDDR1 kinase domain + cancer drug
6few – hDDR1 kinase domain + alport syndrome drug
6fex, 6fil, 6fim, 6fin, 6fio, 6fiq – hDDR1 kinase domain (mutant) + alport syndrome drug
4ckr, 5bvn, 5bvo, 5bvw, 5fdp, 5fdx, 6brj, 6gwr – hDDR1 kinase domain + inhibitor
4ag4 – hDDR1 29-367 domain + antibody
References
- ↑ Roberts ME, Magowan L, Hall IP, Johnson SR. Discoidin domain receptor 1 regulates bronchial epithelial repair and matrix metalloproteinase production. Eur Respir J. 2011 Jun;37(6):1482-93. doi: 10.1183/09031936.00039710. Epub 2010, Sep 30. PMID:20884741 doi:http://dx.doi.org/10.1183/09031936.00039710
- ↑ 2.0 2.1 Borza CM, Pozzi A. Discoidin domain receptors in disease. Matrix Biol. 2014 Feb;34:185-92. doi: 10.1016/j.matbio.2013.12.002. Epub 2013 Dec, 19. PMID:24361528 doi:http://dx.doi.org/10.1016/j.matbio.2013.12.002
- ↑ Song J, Chen X, Bai J, Liu Q, Li H, Xie J, Jing H, Zheng J. Discoidin domain receptor 1 (DDR1), a promising biomarker, induces epithelial to mesenchymal transition in renal cancer cells. Tumour Biol. 2016 Aug;37(8):11509-21. doi: 10.1007/s13277-016-5021-2. Epub 2016, Mar 28. PMID:27020590 doi:http://dx.doi.org/10.1007/s13277-016-5021-2
- ↑ Toy KA, Valiathan RR, Nunez F, Kidwell KM, Gonzalez ME, Fridman R, Kleer CG. Tyrosine kinase discoidin domain receptors DDR1 and DDR2 are coordinately deregulated in triple-negative breast cancer. Breast Cancer Res Treat. 2015 Feb;150(1):9-18. doi: 10.1007/s10549-015-3285-7., Epub 2015 Feb 10. PMID:25667101 doi:http://dx.doi.org/10.1007/s10549-015-3285-7
Proteopedia Page Contributors and Editors (what is this?)
Michal Harel, Alexander Berchansky, Joel L. Sussman, Jaime Prilusky
