6ixr
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==Structure of Myo2-GTD in complex with Inp2== | |
| - | + | <StructureSection load='6ixr' size='340' side='right' caption='[[6ixr]], [[Resolution|resolution]] 2.85Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[6ixr]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6IXR OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6IXR FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6ixr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6ixr OCA], [http://pdbe.org/6ixr PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6ixr RCSB], [http://www.ebi.ac.uk/pdbsum/6ixr PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6ixr ProSAT]</span></td></tr> |
| + | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/MYO2_YEAST MYO2_YEAST]] Myosin heavy chain that is required for the cell cycle-regulated transport of various organelles and proteins for their segregation. Functions by binding with its tail domain to receptor proteins on organelles and exerting force with its N-terminal motor domain against actin filaments, thereby transporting its cargo along polarized actin cables. Essential for the delivery of secretory vesicles to sites of active growth during bud emergence and cytokinesis. Required for segregation and inheritance of peroxisomes, late Golgi compartments, mitochondria and the vacuole to the daughter cell during cell division. Also required for correct alignment of the spindle during mitosis.<ref>PMID:10931864</ref> <ref>PMID:11285273</ref> <ref>PMID:11381095</ref> <ref>PMID:11733545</ref> <ref>PMID:11781333</ref> <ref>PMID:12391144</ref> <ref>PMID:12743102</ref> <ref>PMID:21248204</ref> [[http://www.uniprot.org/uniprot/INP2_YEAST INP2_YEAST]] Required for peroxisome inheritance. Acts as the peroxisome-specific receptor for the myosin V motor MYO2.<ref>PMID:16678774</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Tang, K]] | ||
| + | [[Category: Wei, Z]] | ||
| + | [[Category: Cargo binding domain]] | ||
| + | [[Category: Protein binding]] | ||
Revision as of 07:31, 6 March 2019
Structure of Myo2-GTD in complex with Inp2
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