3kx1

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==Cathepsin K in complex with a selective 2-cyano-pyrimidine inhibitor==
==Cathepsin K in complex with a selective 2-cyano-pyrimidine inhibitor==
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<StructureSection load='3kx1' size='340' side='right' caption='[[3kx1]], [[Resolution|resolution]] 1.51&Aring;' scene=''>
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<StructureSection load='3kx1' size='340' side='right'caption='[[3kx1]], [[Resolution|resolution]] 1.51&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3kx1]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KX1 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3KX1 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3kx1]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KX1 OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=3KX1 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=KX1:4-CYCLOHEPTYL-6-(3-PIPERIDIN-1-YLPROPYL)PYRIMIDINE-2-CARBONITRILE'>KX1</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=KX1:4-CYCLOHEPTYL-6-(3-PIPERIDIN-1-YLPROPYL)PYRIMIDINE-2-CARBONITRILE'>KX1</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3kwz|3kwz]]</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3kwz|3kwz]]</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Cathepsin_K Cathepsin K], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.22.38 3.4.22.38] </span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Cathepsin_K Cathepsin K], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.22.38 3.4.22.38] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3kx1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3kx1 OCA], [http://pdbe.org/3kx1 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3kx1 RCSB], [http://www.ebi.ac.uk/pdbsum/3kx1 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3kx1 ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=3kx1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3kx1 OCA], [http://pdbe.org/3kx1 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3kx1 RCSB], [http://www.ebi.ac.uk/pdbsum/3kx1 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3kx1 ProSAT]</span></td></tr>
</table>
</table>
== Disease ==
== Disease ==
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==See Also==
==See Also==
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*[[Cathepsin|Cathepsin]]
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*[[Cathepsin 3D structures|Cathepsin 3D structures]]
== References ==
== References ==
<references/>
<references/>
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[[Category: Cathepsin K]]
[[Category: Cathepsin K]]
[[Category: Human]]
[[Category: Human]]
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[[Category: Large Structures]]
[[Category: Fradera, X]]
[[Category: Fradera, X]]
[[Category: Uitdehaag, J C.M]]
[[Category: Uitdehaag, J C.M]]

Revision as of 07:04, 7 October 2020

Cathepsin K in complex with a selective 2-cyano-pyrimidine inhibitor

PDB ID 3kx1

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