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3lee
From Proteopedia
(Difference between revisions)
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==Crystal structure of the human squalene synthase complexed with BPH-652== | ==Crystal structure of the human squalene synthase complexed with BPH-652== | ||
| - | <StructureSection load='3lee' size='340' side='right' caption='[[3lee]], [[Resolution|resolution]] 3.20Å' scene=''> | + | <StructureSection load='3lee' size='340' side='right'caption='[[3lee]], [[Resolution|resolution]] 3.20Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[3lee]] is a 6 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[3lee]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LEE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3LEE FirstGlance]. <br> |
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=B65:(1R)-4-(3-PHENOXYPHENYL)-1-PHOSPHONOBUTANE-1-SULFONIC+ACID'>B65</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr> | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=B65:(1R)-4-(3-PHENOXYPHENYL)-1-PHOSPHONOBUTANE-1-SULFONIC+ACID'>B65</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr> |
| - | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">FDFT1 ([ | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">FDFT1 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr> |
| - | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Squalene_synthase Squalene synthase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.5.1.21 2.5.1.21] </span></td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3lee FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3lee OCA], [https://pdbe.org/3lee PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3lee RCSB], [https://www.ebi.ac.uk/pdbsum/3lee PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3lee ProSAT]</span></td></tr> |
</table> | </table> | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Human]] | [[Category: Human]] | ||
| + | [[Category: Large Structures]] | ||
[[Category: Squalene synthase]] | [[Category: Squalene synthase]] | ||
[[Category: Lin, F Y]] | [[Category: Lin, F Y]] | ||
Revision as of 13:40, 4 May 2022
Crystal structure of the human squalene synthase complexed with BPH-652
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Categories: Human | Large Structures | Squalene synthase | Lin, F Y | Liu, Y L | Oldfield, E | Cholesterol biosynthesis | Endoplasmic reticulum | Isoprene biosynthesis | Isoprenoid synthase fold | Lipid synthesis | Magnesium | Membrane | Multifunctional enzyme | Nadp | Oxidoreductase | Steroid biosynthesis | Sterol biosynthesis | Transferase | Transmembrane
