This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
Alkaline phosphatase
From Proteopedia
(Difference between revisions)
| Line 18: | Line 18: | ||
*<scene name='47/471754/Cv/4'>Zn cluster</scene>. | *<scene name='47/471754/Cv/4'>Zn cluster</scene>. | ||
*<scene name='47/471754/Cv/5'>Mg+2 coordination site</scene>. | *<scene name='47/471754/Cv/5'>Mg+2 coordination site</scene>. | ||
| + | |||
| + | == 3D Structures of alkaline phosphatase == | ||
| + | [[Alkaline phosphatase 3D structures]] | ||
| + | |||
</StructureSection> | </StructureSection> | ||
== 3D Structures of alkaline phosphatase == | == 3D Structures of alkaline phosphatase == | ||
| Line 43: | Line 47: | ||
**[[3e2d]] – ALP + Zn + Mg – ''Vibrio''<br /> | **[[3e2d]] – ALP + Zn + Mg – ''Vibrio''<br /> | ||
**[[3a52]] - ALP + Zn + Mg – ''Shewanella''<br /> | **[[3a52]] - ALP + Zn + Mg – ''Shewanella''<br /> | ||
| - | **[[3q3q]] - | + | **[[3q3q]] - SpALP + Zn + Ca – ''Sphingomonas''<br /> |
**[[2yeq]] - ALP D + Fe + Ca – ''Bacillus subtilis''<br /> | **[[2yeq]] - ALP D + Fe + Ca – ''Bacillus subtilis''<br /> | ||
**[[3zwu]] - PfALP Phox + Fe2O + VO4 – ''Pseudomonas fluorescens''<br /> | **[[3zwu]] - PfALP Phox + Fe2O + VO4 – ''Pseudomonas fluorescens''<br /> | ||
| Line 74: | Line 78: | ||
**[[5jk4]] - ALP + phosphate - ''Stenotrophomonas maltophilia'' <br /> | **[[5jk4]] - ALP + phosphate - ''Stenotrophomonas maltophilia'' <br /> | ||
**[[5tj3]] - EmALP + Zn + phosphothreonine – ''Elizabethkingia meningoseptica''<br /> | **[[5tj3]] - EmALP + Zn + phosphothreonine – ''Elizabethkingia meningoseptica''<br /> | ||
| + | **[[5xwi]] - SpALP + Zn + Ca + phosphothreonine<br /> | ||
| + | **[[5xwk]] - SpALP + Zn + Ca + phosphate<br /> | ||
*ALP complexes | *ALP complexes | ||
| Line 79: | Line 85: | ||
**[[2mlx]], [[2mly]], [[2mlz]] - EcALP residues 220-310 + trigger factor - NMR<br /> | **[[2mlx]], [[2mly]], [[2mlz]] - EcALP residues 220-310 + trigger factor - NMR<br /> | ||
**[[5jtl]] – EcALP + SecB<br /> | **[[5jtl]] – EcALP + SecB<br /> | ||
| + | **[[5jtn]] – EcALP residues 91-145 + SecB<br /> | ||
| + | **[[5jto]] – EcALP residues 271-310 + SecB<br /> | ||
**[[5too]] - EmALP (mutant) + Zn <br /> | **[[5too]] - EmALP (mutant) + Zn <br /> | ||
| + | |||
}} | }} | ||
== References == | == References == | ||
<references/> | <references/> | ||
[[Category:Topic Page]] | [[Category:Topic Page]] | ||
Revision as of 10:38, 5 March 2019
| |||||||||||
3D Structures of alkaline phosphatase
Updated on 05-March-2019
References
- ↑ Llinas P, Stura EA, Menez A, Kiss Z, Stigbrand T, Millan JL, Le Du MH. Structural studies of human placental alkaline phosphatase in complex with functional ligands. J Mol Biol. 2005 Jul 15;350(3):441-51. PMID:15946677 doi:http://dx.doi.org/10.1016/j.jmb.2005.04.068
- ↑ Stec B, Hehir MJ, Brennan C, Nolte M, Kantrowitz ER. Kinetic and X-ray structural studies of three mutant E. coli alkaline phosphatases: insights into the catalytic mechanism without the nucleophile Ser102. J Mol Biol. 1998 Apr 3;277(3):647-62. PMID:9533886 doi:10.1006/jmbi.1998.1635
