3mex

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==Crystal structure of MexR in oxidized state==
==Crystal structure of MexR in oxidized state==
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<StructureSection load='3mex' size='340' side='right' caption='[[3mex]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
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<StructureSection load='3mex' size='340' side='right'caption='[[3mex]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3mex]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Pseae Pseae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3MEX OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3MEX FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3mex]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_aeruginosa_PAO1 Pseudomonas aeruginosa PAO1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3MEX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3MEX FirstGlance]. <br>
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</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1lnw|1lnw]], [[3ech|3ech]]</td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1&#8491;</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">MEXR ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=208964 PSEAE])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3mex FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3mex OCA], [https://pdbe.org/3mex PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3mex RCSB], [https://www.ebi.ac.uk/pdbsum/3mex PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3mex ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3mex FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3mex OCA], [http://pdbe.org/3mex PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3mex RCSB], [http://www.ebi.ac.uk/pdbsum/3mex PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3mex ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/MEXR_PSEAE MEXR_PSEAE]] Repressor of the mexAB-oprM multidrug resistance operon. Also represses its own expression. Many variants lead to increased expression of the mexAB-oprM operon.
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[https://www.uniprot.org/uniprot/MEXR_PSEAE MEXR_PSEAE] Repressor of the mexAB-oprM multidrug resistance operon. Also represses its own expression. Many variants lead to increased expression of the mexAB-oprM operon.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Pseae]]
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[[Category: Large Structures]]
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[[Category: Chen, H]]
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[[Category: Pseudomonas aeruginosa PAO1]]
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[[Category: He, C]]
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[[Category: Chen H]]
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[[Category: Yang, C G]]
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[[Category: He C]]
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[[Category: Yi, C]]
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[[Category: Yang C-G]]
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[[Category: Zhang, J]]
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[[Category: Yi C]]
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[[Category: Zhang, W]]
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[[Category: Zhang J]]
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[[Category: Antibiotics resistance regulation]]
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[[Category: Zhang W]]
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[[Category: Dna-binding]]
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[[Category: Oxidative stress]]
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[[Category: Thiol modification]]
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[[Category: Transcription]]
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[[Category: Transcription regulation]]
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Revision as of 16:32, 1 November 2023

Crystal structure of MexR in oxidized state

PDB ID 3mex

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OCA

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