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6mst
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==Cryo-EM structure of human AA amyloid fibril== | |
| - | + | <StructureSection load='6mst' size='340' side='right'caption='[[6mst]], [[Resolution|resolution]] 2.70Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[6mst]] is a 12 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6MST OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6MST FirstGlance]. <br> | |
| - | + | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6mst FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6mst OCA], [http://pdbe.org/6mst PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6mst RCSB], [http://www.ebi.ac.uk/pdbsum/6mst PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6mst ProSAT]</span></td></tr> | |
| - | [[Category: | + | </table> |
| + | == Disease == | ||
| + | [[http://www.uniprot.org/uniprot/SAA1_HUMAN SAA1_HUMAN]] Secondary amyloidosis. Reactive, secondary amyloidosis is characterized by the extracellular accumulation in various tissues of the SAA1 protein. These deposits are highly insoluble and resistant to proteolysis; they disrupt tissue structure and compromise function. Elevated serum SAA1 protein levels may be associated with lung cancer. | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/SAA1_HUMAN SAA1_HUMAN]] Major acute phase reactant. Apolipoprotein of the HDL complex. | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Fandrich, M]] | ||
| + | [[Category: Grigorieff, N]] | ||
| + | [[Category: Liberta, F]] | ||
| + | [[Category: Loerch, S]] | ||
| + | [[Category: Rennegarbe, M]] | ||
| + | [[Category: Schmidt, M]] | ||
| + | [[Category: Aa-amyloidosis]] | ||
| + | [[Category: Cross-beta]] | ||
| + | [[Category: Helical]] | ||
| + | [[Category: Protein fibril]] | ||
| + | [[Category: Serum amyloid some]] | ||
Revision as of 12:08, 13 March 2019
Cryo-EM structure of human AA amyloid fibril
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