6qec

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m (Protected "6qec" [edit=sysop:move=sysop])
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'''Unreleased structure'''
 
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The entry 6qec is ON HOLD until Paper Publication
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==DNA binding domain of LUX ARRYTHMO in complex with DNA==
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<StructureSection load='6qec' size='340' side='right'caption='[[6qec]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
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Authors: Zubieta, C., Nayak, A.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[6qec]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6QEC OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6QEC FirstGlance]. <br>
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Description: DNA binding domain of LUX ARRYTHMO in complex with DNA
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
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[[Category: Unreleased Structures]]
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5lxu|5lxu]]</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6qec FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6qec OCA], [http://pdbe.org/6qec PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6qec RCSB], [http://www.ebi.ac.uk/pdbsum/6qec PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6qec ProSAT]</span></td></tr>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/PCL1_ARATH PCL1_ARATH]] Transcription factor that is essential for the generation of the circadian clock oscillation. Is necessary for activation of CCA1 and LHY expression. Is coregulated with TOC1 and seems to be repressed by CCA1 and LHY by direct binding of these proteins to the evening element in the LUX promoter. Directly regulates the expression of PRR9, a major component of the morning transcriptional feedback circuit, by binding specific sites on PRR9 promoter. Binds to its own promoter, inducing a negative auto-regulatory feedback loop within the core clock. Binds to ELF3 and associates with ELF4 in a diurnal complex which is required for the expression of the growth-promoting transcription factors PIF4 and PIF5 and subsequent hypocotyl growth in the early evening.<ref>PMID:16006522</ref> <ref>PMID:16164597</ref> <ref>PMID:21236673</ref> <ref>PMID:21753751</ref> <ref>PMID:22311777</ref>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
[[Category: Nayak, A]]
[[Category: Nayak, A]]
[[Category: Zubieta, C]]
[[Category: Zubieta, C]]
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[[Category: Circadian clock protein]]
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[[Category: Protein-dna complex myb domain]]

Revision as of 08:04, 5 February 2020

DNA binding domain of LUX ARRYTHMO in complex with DNA

PDB ID 6qec

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