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6cgc

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==Crystal structure of human 17beta-HSD type 1 in ternary complex with 2-MeO-CC-156 and NADP+==
==Crystal structure of human 17beta-HSD type 1 in ternary complex with 2-MeO-CC-156 and NADP+==
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<StructureSection load='6cgc' size='340' side='right' caption='[[6cgc]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
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<StructureSection load='6cgc' size='340' side='right'caption='[[6cgc]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[6cgc]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6CGC OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6CGC FirstGlance]. <br>
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<table><tr><td colspan='2'>[[6cgc]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6CGC OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=6CGC FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=F0A:3-{[(9beta,14beta,16alpha,17alpha)-3,17-dihydroxy-2-methoxyestra-1,3,5(10)-trien-16-yl]methyl}benzamide'>F0A</scene>, <scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=F0A:3-{[(9beta,14beta,16alpha,17alpha)-3,17-dihydroxy-2-methoxyestra-1,3,5(10)-trien-16-yl]methyl}benzamide'>F0A</scene>, <scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/17-beta-estradiol_17-dehydrogenase 17-beta-estradiol 17-dehydrogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.62 1.1.1.62] </span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/17-beta-estradiol_17-dehydrogenase 17-beta-estradiol 17-dehydrogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.62 1.1.1.62] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6cgc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6cgc OCA], [http://pdbe.org/6cgc PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6cgc RCSB], [http://www.ebi.ac.uk/pdbsum/6cgc PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6cgc ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=6cgc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6cgc OCA], [http://pdbe.org/6cgc PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6cgc RCSB], [http://www.ebi.ac.uk/pdbsum/6cgc PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6cgc ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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</div>
</div>
<div class="pdbe-citations 6cgc" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 6cgc" style="background-color:#fffaf0;"></div>
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==See Also==
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*[[Hydroxysteroid dehydrogenase 3D structures|Hydroxysteroid dehydrogenase 3D structures]]
== References ==
== References ==
<references/>
<references/>
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</StructureSection>
</StructureSection>
[[Category: 17-beta-estradiol 17-dehydrogenase]]
[[Category: 17-beta-estradiol 17-dehydrogenase]]
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[[Category: Large Structures]]
[[Category: Li, T]]
[[Category: Li, T]]
[[Category: Lin, S X]]
[[Category: Lin, S X]]

Revision as of 08:56, 11 November 2020

Crystal structure of human 17beta-HSD type 1 in ternary complex with 2-MeO-CC-156 and NADP+

PDB ID 6cgc

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