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3ngp

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Current revision (09:15, 6 September 2023) (edit) (undo)
 
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==High resolution structure of alpha-spectrin SH3 domain mutant with a redesigned core==
==High resolution structure of alpha-spectrin SH3 domain mutant with a redesigned core==
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<StructureSection load='3ngp' size='340' side='right' caption='[[3ngp]], [[Resolution|resolution]] 1.08&Aring;' scene=''>
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<StructureSection load='3ngp' size='340' side='right'caption='[[3ngp]], [[Resolution|resolution]] 1.08&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3ngp]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Chick Chick]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NGP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3NGP FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3ngp]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NGP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3NGP FirstGlance]. <br>
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</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1shg|1shg]]</td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.084&#8491;</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">SPTAN1, SPTA2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9031 CHICK])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ngp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ngp OCA], [https://pdbe.org/3ngp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ngp RCSB], [https://www.ebi.ac.uk/pdbsum/3ngp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ngp ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ngp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ngp OCA], [http://pdbe.org/3ngp PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3ngp RCSB], [http://www.ebi.ac.uk/pdbsum/3ngp PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3ngp ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/SPTN1_CHICK SPTN1_CHICK]] Morphologically, spectrin-like proteins appear to be related to spectrin, showing a flexible rod-like structure. They can bind actin but seem to differ in their calmodulin-binding activity. In nonerythroid tissues, spectrins, in association with some other proteins, may play an important role in membrane organization.
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[https://www.uniprot.org/uniprot/SPTN1_CHICK SPTN1_CHICK] Morphologically, spectrin-like proteins appear to be related to spectrin, showing a flexible rod-like structure. They can bind actin but seem to differ in their calmodulin-binding activity. In nonerythroid tissues, spectrins, in association with some other proteins, may play an important role in membrane organization.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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==See Also==
==See Also==
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*[[Spectrin|Spectrin]]
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*[[Spectrin 3D structures|Spectrin 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Chick]]
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[[Category: Gallus gallus]]
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[[Category: Camara-Artigas, A]]
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[[Category: Large Structures]]
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[[Category: Gavira, J A]]
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[[Category: Camara-Artigas A]]
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[[Category: Martin-Garcia, J M]]
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[[Category: Gavira JA]]
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[[Category: Beta barrel]]
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[[Category: Martin-Garcia JM]]
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[[Category: Structural protein]]
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Current revision

High resolution structure of alpha-spectrin SH3 domain mutant with a redesigned core

PDB ID 3ngp

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