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6qf4
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==X-Ray structure of human Serine/Threonine Kinase 17B (STK17B) aka DRAK2 in complex with ADP obtained by on-chip soaking== | |
| - | + | <StructureSection load='6qf4' size='340' side='right'caption='[[6qf4]], [[Resolution|resolution]] 2.50Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[6qf4]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6QF4 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6QF4 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr> | |
| - | [[Category: | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[6qf1|6qf1]], [[6qf2|6qf2]], [[6qf3|6qf3]]</td></tr> |
| - | [[Category: | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Non-specific_serine/threonine_protein_kinase Non-specific serine/threonine protein kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.1 2.7.11.1] </span></td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6qf4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6qf4 OCA], [http://pdbe.org/6qf4 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6qf4 RCSB], [http://www.ebi.ac.uk/pdbsum/6qf4 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6qf4 ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/ST17B_HUMAN ST17B_HUMAN]] Phosphorylates myosin light chains (By similarity). Acts as a positive regulator of apoptosis.<ref>PMID:9786912</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Non-specific serine/threonine protein kinase]] | ||
| + | [[Category: Barthelmess, M]] | ||
| + | [[Category: Bergtholdt, J]] | ||
| + | [[Category: Burkhardt, A]] | ||
| + | [[Category: Cerv, M]] | ||
| + | [[Category: Chapman, H N]] | ||
[[Category: Crosas, E]] | [[Category: Crosas, E]] | ||
| + | [[Category: Fischer, P]] | ||
| + | [[Category: Guenther, S]] | ||
| + | [[Category: Kreida, S]] | ||
| + | [[Category: Lane, T J]] | ||
| + | [[Category: Lieske, J]] | ||
[[Category: Lorbeer, O]] | [[Category: Lorbeer, O]] | ||
| - | [[Category: | + | [[Category: Mariani, V]] |
| + | [[Category: Meents, A]] | ||
| + | [[Category: Pakendorf, T]] | ||
| + | [[Category: Ross, B H]] | ||
| + | [[Category: Schoen, S]] | ||
[[Category: Seine, T]] | [[Category: Seine, T]] | ||
| - | [[Category: Chapman, H.N]] | ||
| - | [[Category: Burkhardt, A]] | ||
| - | [[Category: Cerv, M]] | ||
[[Category: Tornroth-Horsefield, S]] | [[Category: Tornroth-Horsefield, S]] | ||
| - | [[Category: Pakendorf, T]] | ||
| - | [[Category: Ross, B.H]] | ||
[[Category: Yefanov, O]] | [[Category: Yefanov, O]] | ||
| - | [[Category: | + | [[Category: Adp]] |
| - | [[Category: | + | [[Category: Drak2]] |
| - | [[Category: | + | [[Category: On-chip ligand soaking]] |
| - | [[Category: | + | [[Category: Stk17b]] |
| - | [[Category: | + | [[Category: Transferase]] |
| - | + | ||
| - | + | ||
| - | + | ||
Revision as of 05:54, 10 July 2019
X-Ray structure of human Serine/Threonine Kinase 17B (STK17B) aka DRAK2 in complex with ADP obtained by on-chip soaking
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Categories: Large Structures | Non-specific serine/threonine protein kinase | Barthelmess, M | Bergtholdt, J | Burkhardt, A | Cerv, M | Chapman, H N | Crosas, E | Fischer, P | Guenther, S | Kreida, S | Lane, T J | Lieske, J | Lorbeer, O | Mariani, V | Meents, A | Pakendorf, T | Ross, B H | Schoen, S | Seine, T | Tornroth-Horsefield, S | Yefanov, O | Adp | Drak2 | On-chip ligand soaking | Stk17b | Transferase
