6f9k
From Proteopedia
(Difference between revisions)
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==Tryptophan Repressor TrpR from E.coli with 5-methyl-L-tryptophan as ligand== | ==Tryptophan Repressor TrpR from E.coli with 5-methyl-L-tryptophan as ligand== | ||
| - | <StructureSection load='6f9k' size='340' side='right' caption='[[6f9k]], [[Resolution|resolution]] 1.40Å' scene=''> | + | <StructureSection load='6f9k' size='340' side='right'caption='[[6f9k]], [[Resolution|resolution]] 1.40Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[6f9k]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6F9K OCA]. For a <b>guided tour on the structure components</b> use [ | + | <table><tr><td colspan='2'>[[6f9k]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6F9K OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6F9K FirstGlance]. <br> |
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=D0Q:5-methyl-L-tryptophan'>D0Q</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.399Å</td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=D0Q:5-methyl-L-tryptophan'>D0Q</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6f9k FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6f9k OCA], [https://pdbe.org/6f9k PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6f9k RCSB], [https://www.ebi.ac.uk/pdbsum/6f9k PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6f9k ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
| - | [ | + | [https://www.uniprot.org/uniprot/TRPR_ECOLI TRPR_ECOLI] This protein is an aporepressor. When complexed with L-tryptophan it binds the operator region of the trp operon (5'-ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region. |
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Escherichia coli K-12]] |
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: | + | [[Category: Hocker B]] |
| - | [[Category: | + | [[Category: Shanmugaratnam S]] |
| - | [[Category: | + | [[Category: Stiel AC]] |
Current revision
Tryptophan Repressor TrpR from E.coli with 5-methyl-L-tryptophan as ligand
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